SSTR2 Antikörper (Extracellular, N-Term)

Produktnummer ABIN7887141

Der Kaninchen Polyklonal anti-SSTR2 Antikörper wird verwendet zum Nachweis von SSTR2 in Proben von Ratte. Er wurde validiert für WB, IHC, FACS, IF, LCI und IC.

Kurzübersicht für SSTR2 Antikörper (Extracellular, N-Term) (ABIN7887141)

Target: SSTR2 (Somatostatin Receptor 2 (SSTR2))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SSTR2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF), Live Cell Imaging (LCI), Immunochromatography (IC)

Produktdetails anti-SSTR2 Antikörper

Bindungsspezifität: AA 30-43, Extracellular, N-Term

Verwendungszweck: A Rabbit Polyclonal Antibody to Somatostatin Receptor Type 2

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Mouse - identical, human- 12,14 amino acid residues identical

Produktmerkmale: Anti-Somatostatin Receptor Type 2 (extracellular) Antibody is directed against the N-terminal domain of the rat SSTR2. Anti-Somatostatin Receptor Type 2 (extracellular) Antibody (ABIN7043765, ABIN7045268 and ABIN7045269), can be used in western blot, immunohistochemistry and immunocytochemistry applications. It has been designed to recognize SSTR2 from mouse, human and rat samples.

Aufreinigung: Affinity purified on immobilized antigen.

Immunogen: (C)GSNQTEPYYDMTSN, corresponding to amino acid residues 30-43 of rat SSTR2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

WB: 1:200

FC: 5 mg per reaction

ICC: 1:50

IHC: 1:100

IP: The optimal concentration should be determined by the user

Kommentare:

Cited Application: IHC

Negative Control: (ABIN7237239)

Blocking Peptide: (ABIN7237239)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: 25 μL, 50 μL or 0.2 mL double distilled water (DDW), depending on the sample size.

Konzentration: 0.8 mg/mL

Buffer: PBS pH 7.4, 1 % BSA with 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C

Details zu SSTR2

Target: SSTR2 (Somatostatin Receptor 2 (SSTR2))

Andere Bezeichnung: SSTR2

Hintergrund:

Synonyms: SSTR2, SS2R, Smstr2, SRIF1A

Description: Somatostatin is a small cyclic peptide that is widely expressed throughout the central nervous system and peripheral tissues.1 In peripheral tissues, somatostatin exerts inhibitory effects on secretion processes, whereas in the brain, it acts as a neurotransmitter in both a stimulatory and an inhibitory manner.1,2Somatostatin mediates its action via six high affinity G-protein coupled receptors (SSTR1, SSTR2a, SSTR2b, SSTR3, SSTR4, and SSTR5), which are encoded by five genes.1,2 Expression of the different receptors is developmentally regulated in a time- and tissue-specific manner.2Somatostatin receptors have been found on a variety of neuroendocrine tumors, such as paragangliomas, carcinoids, and breast tumors.3 Synthetic peptide derivatives of somatostatin have been successfully used in the treatment of neuroendocrine malignancies and in vivo imaging of tumors that are positive for somatostatin receptors.4In general, SSTR2 is the most common SSTR subtype found in human tumors, followed by SSTR1, with SSTR3 and SSTR4 being less common.

Gen-ID: 54305

NCBI Accession: NM_001050

UniProt: P30680