ENPP2 Antikörper

Produktnummer ABIN7581209

Produktdetails anti-ENPP2 Antikörper

Target: ENPP2 (Ectonucleotide Pyrophosphatase/phosphodiesterase 2 (ENPP2))

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser ENPP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Verwendungszweck: Goat polycolonal antibody targeting human Autotaxin (ATX)

Spezifität: Anti-ATX antibody recognizes endogenous human ATX and is predicted to recognize rat, mouse, horse, and feline ATX based on amino acid conservation.

Aufreinigung: affinity purified

Immunogen: ATX peptide

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB – 1:1000, ELISA – 1:1000 Other in vitro and cellular applications are possible using this antibody, but have not been verified.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Antibody is stable for up to 1 year at -20°C. Antibody is stable at 4°C for up to 60 days. Avoid repeated freeze/thaw cycles.

Details zu ENPP2

Target: ENPP2 (Ectonucleotide Pyrophosphatase/phosphodiesterase 2 (ENPP2))

Andere Bezeichnung: Autotaxin (ENPP2 Produkte)

Hintergrund: ATX, also known as ENPP2, cleaves choline from lysophosphatidylcholine forming lysophosphatidic acid (LPA), a potent mitogen that has been implicated in the pathophysiology of ovarian cancer. ATX has been demonstrated to increase cell motility, neovascularization, proliferation, and aggressiveness of tumors and is upregulated in numerous cancer lineages (non-small cell lung , glioma, mammary carcinoma, renal cell carcinoma, hepatocellular carcinoma). In addition, dysregulation of the ATX/LPA pathway is central to the pathophysiology of idiopathic pulmonary fibrosis, rheumatoid arthritis, and other inflammatory diseases.