DGKA Antikörper

Produktnummer ABIN7581173

Produktdetails anti-DGKA Antikörper

Target: DGKA (Diacylglycerol Kinase, alpha 80kDa (DGKA))

Reaktivität: Human

Wirt: Schaf

Klonalität: Polyklonal

Konjugat: Dieser DGKA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Sheep polyclonal antibody against diacylglycerol kinase α (DGKα)

Spezifität: This antibody recognizes the alpha isoform of diacylglycerol kinase (DGK). DGK catalyzes a reaction terminating the protein kinase C mediated signaling by converting diacylglycerol (DAG) to phosphatidic acid (PA), a signaling lipid which is involved in DNA synthesis, phospholipid synthesis, and regulation of several enzymes.

Kreuzreaktivität (Details): Shown to recognize an 80-85kDa recombinant DGKα protein with non-specific cross activity to wild-type DGK ζ protein.

Aufreinigung: Serum

Immunogen: peptide = MAKERGLISPSDFAQL

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB – 1:1000 Other in vitro and cellular applications are possible using this antibody, but have not been verified.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 0.01% thiomersal

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4 °C for up to 30 days. Aliquot and store at -20 °C if longer storage is necessary. Antibody is stable for at least 2 years when stored at -20 °C. Avoid repeated freeze/thaw cycles.

Details zu DGKA

Target: DGKA (Diacylglycerol Kinase, alpha 80kDa (DGKA))

Andere Bezeichnung: DGK Alpha (DGKA Produkte)

Hintergrund: DGK catalyzes a reaction terminating the protein kinase C (PKC)mediated signaling by converting diacylglycerol (DAG) to phosphatidic acid (PA), a signaling lipid which is involved in DNA synthesis, phospholipid synthesis, and regulation of several enzymes. DAG is an intermediate in phospholipid synthesis which functions as an allosteric activator of PKC. The alpha isoform is a type I DGKs, and has slightly different calcium-responsiveness.