AKT 1/2/3 Antikörper (AA 401-479) (Cy5)
-
- Target Alle AKT 1/2/3 Produkte
- AKT 1/2/3
-
Bindungsspezifität
- AA 401-479
-
Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Schwein
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser AKT 1/2/3 Antikörper ist konjugiert mit Cy5
-
Applikation
- Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Rind (Kuh), Human, Maus, Schwein, Ratte
- Homologie
- Dog,Cow,Sheep,Chicken
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human AKT1
- Isotyp
- IgG
-
anti-AKT 1/2/3 (AA 401-479) antibody
Reaktivität: Human, Maus, Ratte, Rind (Kuh), Schwein WB, FACS, IF (cc), ELISA, IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-AKT 1/2/3 (pSer473) antibodyReaktivität: Human, Maus, Ratte, Rind (Kuh), Kaninchen, Huhn, Fisch WB, IF (cc), ELISA, IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-AKT 1/2/3 antibodyReaktivität: Human WB, IHC, IF, IP Wirt: Kaninchen Polyclonal unconjugated
anti-AKT 1/2/3 (pSer472) antibodyReaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-AKT 1/2/3 antibodyReaktivität: Human, Maus, Ratte, Schimpanse WB, IHC, FACS, ELISA Wirt: Maus Monoclonal 14E5-16C8-25F6 unconjugated
anti-AKT 1/2/3 (pTyr312), (pTyr315), (pTyr316) antibodyReaktivität: Human, Maus, Ratte WB, FACS, IF (cc), ELISA, IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-AKT 1/2/3 (pTyr474) antibodyReaktivität: Human, Maus WB, FACS, IF (cc), ELISA, IF (p), IHC (p), IHC (fro), ICC Wirt: Kaninchen Polyclonal unconjugated
anti-AKT 1/2/3 (pTyr312), (pTyr315), (pTyr316) antibodyReaktivität: Human, Maus, Ratte WB, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-AKT 1/2/3 (pThr305), (pThr308), (pThr309) antibodyReaktivität: Human, Maus, Ratte WB, FACS, IF (cc), ELISA, IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-AKT 1/2/3 (AA 278-312) antibodyReaktivität: Human, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal RB43841 unconjugated
-
- Applikationshinweise
-
FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
-
- Target
- AKT 1/2/3
- Andere Bezeichnung
- AKT1/2/3 (AKT 1/2/3 Produkte)
- Hintergrund
-
Synonyms: AKT, PKB, RAC, CWS6, PRKBA, PKB-ALPHA, RAC-ALPHA, RAC-alpha serine/threonine-protein kinase, Protein kinase B, Protein kinase B alpha, PKB alpha, Proto-oncogene c-Akt, RAC-PK-alpha, AKT1, RAC-gamma serine/threonine-protein kinase, Protein kinase Akt-3, Protein kinase B gamma, PKB gamma, RAC-PK-gamma, STK-2, PKBG
Background: AKT1-specific substrates have been recently identified, including palladin (PALLD), which phosphorylation modulates cytoskeletal organization and cell motility, prohibitin (PHB), playing an important role in cell metabolism and proliferation, and CDKN1A, for which phosphorylation at 'Thr-145' induces its release from CDK2 and cytoplasmic relocalization. These recent findings indicate that the AKT1 isoform has a more specific role in cell motility and proliferation. Phosphorylates CLK2 thereby controlling cell survival to ionizing radiation.
- Gen-ID
- 207
- UniProt
- P31749
-
