Caspase 10 Antikörper (AA 431-521) (FITC)

Produktnummer ABIN724782

Produktdetails anti-Caspase 10 Antikörper (FITC)

Target: Caspase 10 (CASP10) (Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10))

Bindungsspezifität: AA 431-521

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Caspase 10 Antikörper ist konjugiert mit FITC

Applikation: Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Caspase-10

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu Caspase 10

Target: Caspase 10 (CASP10) (Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10))

Andere Bezeichnung: Caspase-10 (CASP10 Produkte)

Synonyme: xCaspase-10 antikoerper, alps2 antikoerper, caspace-10 antikoerper, caspase-10 antikoerper, flice2 antikoerper, mch4 antikoerper, xCaspace-10 antikoerper, ALPS2 antikoerper, FLICE2 antikoerper, MCH4 antikoerper, caspase 10 S homeolog antikoerper, caspase 10 antikoerper, caspase-10 antikoerper, casp10.S antikoerper, casp10 antikoerper, CASP10 antikoerper, Casp10 antikoerper, LOC100848685 antikoerper

Hintergrund:

Synonyms: MCH4, ALPS2, FLICE2, Caspase-10, CASP-10, Apoptotic protease Mch-4, FAS-associated death domain protein interleukin-1B-converting enzyme 2, ICE-like apoptotic protease 4, CASP10

Background: Involved in the activation cascade of caspases responsible for apoptosis execution. Recruited to both Fas- and TNFR-1 receptors in a FADD dependent manner. May participate in the granzyme B apoptotic pathways. Cleaves and activates caspase-3, -4, -6, -7, -8, and -9. Hydrolyzes the small- molecule substrates, Tyr-Val-Ala-Asp-|-AMC and Asp-Glu-Val-Asp-|-AMC. Isoform C is proteolytically inactive.

Gen-ID: 843

UniProt: Q92851

Pathways: Apoptose, Caspase Kaskade in der Apoptose