Caspase 10 Antikörper (AA 431-521)
Kurzübersicht für Caspase 10 Antikörper (AA 431-521) (ABIN724775)
Target
Alle Caspase 10 (CASP10) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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    - 
                                            Bindungsspezifität
- AA 431-521
- 
                                            Kreuzreaktivität
- Human
- 
                                            Aufreinigung
- Purified by Protein A.
- 
                                            Immunogen
- KLH conjugated synthetic peptide derived from human Caspase-10
- 
                                            Isotyp
- IgG
 
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- 
    - 
                                            Applikationshinweise
- 
                        ELISA 1:500-1000
 FCM 1:20-100
 IHC-P 1:200-400
 IHC-F 1:100-500
 IF(IHC-P) 1:50-200
 IF(IHC-F) 1:50-200
 IF(ICC) 1:50-200
- 
                                            Beschränkungen
- Nur für Forschungszwecke einsetzbar
 
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- 
    - 
                                            Format
- Liquid
- 
                                            Konzentration
- 1 μg/μL
- 
                                            Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 
                                            Konservierungsmittel
- ProClin
- 
                                            Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 
                                            Lagerung
- 4 °C,-20 °C
- 
                                            Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 
                                            Haltbarkeit
- 12 months
 
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- 
    - Caspase 10 (CASP10) (Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10))
- 
                                            Andere Bezeichnung
- Caspase-10
- 
                                            Hintergrund
- 
                        Synonyms: MCH4, ALPS2, FLICE2, Caspase-10, CASP-10, Apoptotic protease Mch-4, FAS-associated death domain protein interleukin-1B-converting enzyme 2, ICE-like apoptotic protease 4, CASP10 Background: Involved in the activation cascade of caspases responsible for apoptosis execution. Recruited to both Fas- and TNFR-1 receptors in a FADD dependent manner. May participate in the granzyme B apoptotic pathways. Cleaves and activates caspase-3, -4, -6, -7, -8, and -9. Hydrolyzes the small- molecule substrates, Tyr-Val-Ala-Asp-|-AMC and Asp-Glu-Val-Asp-|-AMC. Isoform C is proteolytically inactive. 
- 
                                            Gen-ID
- 843
- 
                                            UniProt
- Q92851
- 
                                            Pathways
- Apoptose, Caspase Kaskade in der Apoptose
 Target
- 
                    
 
                                     
                                     
                                    