CD47 Antikörper (Elab Fluor®700)

Produktnummer ABIN7566750

Der Maus Monoklonal Anti-CD47-Antikörper wurde für FACS validiert. Er ist geeignet, CD47 in Proben von Human zu detektieren.

Kurzübersicht für CD47 Antikörper (Elab Fluor®700) (ABIN7566750)

Target: CD47

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD47 Antikörper ist konjugiert mit Elab Fluor®700

Applikation: Flow Cytometry (FACS)

Klon: CC2C6D4

Produktdetails anti-CD47 Antikörper (Elab Fluor®700)

Verwendungszweck: Elab Fluor®700 Anti-Human CD47 Antibody[CC2C6D4]

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Each lot of this antibody is quality control tested by flow cytometric analysis. Applications vary, the appropriate dilutions must be determined for individual use.

Kommentare:

Matching Isotype Control: E-AB-F09792M1

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant.

Lagerung: 4 °C

Informationen zur Lagerung: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Haltbarkeit: 12 months

Details zu CD47

Target: CD47

Andere Bezeichnung: CD47

Hintergrund: Cd47,IAP,Integrin-associated protein,Leukocyte surface antigen CD47,CD47 also known as Rh-associated protein, gp42, integrin-associated protein (IAP), and neurophilin, is a 42-52 kD member of the immunoglobulin superfamily containing a five-pass transmembrane attachment. Two splice variants have been described in the cytoplasmic tail, the shorter form is expressed in bone-marrow-derived cells, endothelial cells, and fibroblasts while the longer form is expressed by neural tissues. CD47 expression is widely distributed in hematopoietic cells including thymocytes, T cells, B cells, monocytes, platelets, and erythrocytes as well as epithelial cells, endothelial cells, fibroblasts, and neural tissues. CD47 functions as an adhesion molecule and thrombospondin receptor and is non-covalently associated with β3 integrins CD51/CD61, CD41/CD61. Thrombospondin is a ligand for CD47, in the absence of CD47 mice show defects in host defense and β3 integrin-dependent ligand binding, migration, and cellular activation. CD47 is also part of the Rh complex on erythrocytes.

Gen-ID: 961

UniProt: Q08722