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CD47 Antikörper (AA 241-323)

Name: CD47 Antikörper (AA 241-323)
SKU: ABIN739530
Price: 384.62 EUR
Availability: InStock

CD47 Reaktivität: Maus, Ratte FACS, WB, ELISA, IHC (fro), IF (cc), IF (p), IHC (p) Wirt: Kaninchen Polyclonal unconjugated

Formalin-fixed and paraffin embedded rat tongue tissue labeled with Anti-CD47 MER6 Polyclonal Antibody, unconjugated (ABIN739530) at 1: 200 followed by incubation with conjugated secondary antibody

IHC

Formalin-fixed and paraffin embedded rat tongue tissue labeled with Anti-CD47/MER6 Polyclonal Antibody, Unconjugated at 1:200 followed by conjugation to the secondary antibody

IHC (p)

RSC96 cells probed with CD47/MER6 Polyclonal Antibody, Unconjugated at 1:100 for 30 minutes followed by incubation with a PE conjugated secondary (green) for 30 minutes compared to control cells (blue), secondary only (light blue) and isotype control (orange).

FACS

IHC

4 Abbildungen

(1 reference)

Produktnummer ABIN739530

Datenblatt (PDF)

Target Alle CD47 Antikörper anzeigen

CD47
Bindungsspezifität
15

15

8

8

7

5

4

3

2

2

2

1

1

1

1

1

1

1

1

1
AA 241-323
Reaktivität
123

53

27

6

4

2

2

2

1

1

1

1
Maus, Ratte
Wirt
80

64

10

1
Kaninchen
Passende Sekundärantikörper
Klonalität
79

74

1
Polyklonal
Konjugat
68

13

13

7

5

5

4

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1
Dieser CD47 Antikörper ist unkonjugiert
Applikation
88

85

44

40

35

25

25

18

15

15

13

11

7

5

4

3

3

3

2

2

2

2

2

1

1

1

1
Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität

Maus, Ratte

Homologie

Human,Rabbit

Aufreinigung

Purified by Protein A.

Immunogen

KLH conjugated synthetic peptide derived from human CD47/MER6

Isotyp

IgG

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CD47 Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

1 μg/μL

Buffer

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel

ProClin

Vorsichtsmaßnahmen

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit

12 months
Miedel, Dishowitz, Myers, Dopkin, Yu, Miclau, Marcucio, Ahn, Hankenson: "Disruption of thrombospondin-2 accelerates ischemic fracture healing." in: Journal of orthopaedic research : official publication of the Orthopaedic Research Society, Vol. 31, Issue 6, pp. 935-43, (2013) (PubMed).
Target

CD47

Andere Bezeichnung

CD47/MER6 (CD47 Produkte)

Synonyme

IAP antikoerper, MER6 antikoerper, OA3 antikoerper, 9130415E20Rik antikoerper, AA407862 antikoerper, AI848868 antikoerper, AW108519 antikoerper, B430305P08Rik antikoerper, Itgp antikoerper, CD47/IAP antikoerper, alkaline phosphatase, intestinal antikoerper, CD47 molecule antikoerper, CD47 antigen (Rh-related antigen, integrin-associated signal transducer) antikoerper, Cd47 molecule antikoerper, ALPI antikoerper, CD47 antikoerper, Cd47 antikoerper

Hintergrund

Synonyms: IAP, OA3, MER6, Leukocyte surface antigen CD47, Antigenic surface determinant protein OA3, Integrin-associated protein, Protein MER6, CD47
Background: Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus (By similarity). Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeability changes induced following virus infection.

Gen-ID

961

UniProt

Q08722