CD86 Antikörper (Elab Fluor®Violet 610)

Produktnummer ABIN7566685

Dieser Ratte Monoklonal Antikörper erkennt spezifisch CD86 in FACS. Er zeigt eine Reaktivität gegenüber Maus.

Kurzübersicht für CD86 Antikörper (Elab Fluor®Violet 610) (ABIN7566685)

Target: CD86

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser CD86 Antikörper ist konjugiert mit Elab Fluor®Violet 610

Applikation: Flow Cytometry (FACS)

Klon: GL-1

Produktdetails anti-CD86 Antikörper (Elab Fluor®Violet 610)

Verwendungszweck: Elab Fluor®Violet 610 Anti-Mouse CD86 Antibody[GL-1]

Isotyp: IgG2a, kappa

Anwendungsinformationen

Applikationshinweise: Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10 cells in 100 μL volume].

Kommentare:

Matching Isotype Control: E-AB-F09833T

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant.

Lagerung: 4 °C

Informationen zur Lagerung: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Haltbarkeit: 12 months

Details zu CD86

Target: CD86

Andere Bezeichnung: CD86

Hintergrund: Activation B7-2 antigen,Cd86,ETC-1,Early T-cell costimulatory molecule 1,T-lymphocyte activation antigen CD86,CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is a ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce co-stimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

Gen-ID: 12524

UniProt: P42082

Pathways: T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation