Rekombinanter SARS-CoV-2 Spike S1 Antikörper

Produktnummer ABIN7566479

Der Human Monoklonal Anti-SARS-CoV-2 Spike S1-Antikörper wurde für ELISA, WB und Func validiert. Er ist geeignet, SARS-CoV-2 Spike S1 in Proben von SARS Coronavirus-2 (SARS-CoV-2) zu detektieren.

Kurzübersicht für Rekombinanter SARS-CoV-2 Spike S1 Antikörper (ABIN7566479)

Target: SARS-CoV-2 Spike S1

Antikörpertyp: Recombinant Antibody

Reaktivität: SARS Coronavirus-2 (SARS-CoV-2)

Wirt: Human

Klonalität: Monoklonal

Konjugat: Dieser SARS-CoV-2 Spike S1 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Functional Studies (Func)

Klon: Covi-1

Produktdetails anti-SARS-CoV-2 Spike S1 Antikörper

Verwendungszweck: anti-SARS-CoV-2 Spike Protein S1 mAb (rec.) (blocking) (Covi-1) (preservative free)

Produktmerkmale:

Recombinant Antibody. Recognizes and binds to recombinant SARS-CoV-2 Spike Protein S1. It blocks the interaction of SARS-CoV-2 Spike Protein S1 (RBD) to human ACE2. Detects a different epitope as anti-SARS-CoV-2 Spike Protein S1, mAb (rec.) (blocking) (Covi-2) (Prod. No. AG-27B-6006PF). Applications: ELISA, FUNC (Blocking), WB. Source: HEK 293 cells. Liquid. In PBS. Coronaviruses (CoVs) are enveloped non-segmented positive-sense single-stranded RNA viruses and can infect respiratory, gastrointestinal, hepatic and central nervous system of human and many other wild animals. Recently, a new severe acute respiratory syndrome beta-coronavirus called SARS-CoV-2 (or 2019-nCoV) has emerged, which causes an epidemic of acute respiratory syndrome (called coronavirus human disease 2019 or COVID-19). SARS-CoV-2 shares 79.5 % sequence identity with SARS-CoV and is 96.2 % identical at the genome level to the bat coronavirus BatCoV RaTG133, suggesting it had originated in bats. SARS-CoV-2 contains 4 structural proteins, including Envelope (E), Membrane (M), Nucleocapsid (N) and Spike (S), which is a transmembrane protein, composed of two subunits S1 and S2. The S1 subunit contains a receptor binding domain (RBD), which binds to the cell surface receptor Angiotensin-Converting Enzyme 2 (ACE2) present at the surface of epithelial cells, causing mainly infection of human respiratory cells.

Coronaviruses (CoVs) are enveloped non-segmented positive-sense single-stranded RNA viruses and can infect respiratory, gastrointestinal, hepatic and central nervous system of human and many other wild animals. Recently, a new severe acute respiratory syndrome beta-coronavirus called SARS-CoV-2 (or 2019-nCoV) has emerged, which causes an epidemic of acute respiratory syndrome (called coronavirus human disease 2019 or COVID-19). SARS-CoV-2 shares 79.5 % sequence identity with SARS-CoV and is 96.2 % identical at the genome level to the bat coronavirus BatCoV RaTG133, suggesting it had originated in bats. SARS-CoV-2 contains 4 structural proteins, including Envelope (E), Membrane (M), Nucleocapsid (N) and Spike (S), which is a transmembrane protein, composed of two subunits S1 and S2. The S1 subunit contains a receptor binding domain (RBD), which binds to the cell surface receptor Angiotensin-Converting Enzyme 2 (ACE2) present at the surface of epithelial cells, causing mainly infection of human respiratory cells.

Aufreinigung: Puified

Reinheit: >98 % (SDS-PAGE)

Endotoxin-Niveau: <0.001EU/μg

Immunogen: Recombinant SARS-CoV-2 Spike Protein S1 receptor binding domain.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: In PBS.

Konservierungsmittel: Without preservative

Handhabung: Avoid freeze/thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung:

+4°C

Stable for at least 1 year after receipt when stored at -20°C.

Details zu SARS-CoV-2 Spike S1

Target: SARS-CoV-2 Spike S1

Andere Bezeichnung: SARS-CoV-2 Spike Protein S1

UniProt: P0DTC2