LAG3 Antikörper

Produktnummer ABIN7566432

Dieses Anti-LAG3-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von LAG3 in WB, IHC, IP, ICC, FACS und Func. Geeignet für Human.

Kurzübersicht für LAG3 Antikörper (ABIN7566432)

Target: LAG3 (Lymphocyte-Activation Gene 3 (LAG3))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser LAG3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC), Flow Cytometry (FACS), Functional Studies (Func)

Klon: 17B4

Produktdetails anti-LAG3 Antikörper

Verwendungszweck: anti-LAG-3 (human), mAb (17B4) (blocking) (preservative free)

Produktmerkmale:

Monoclonal Antibody. Recognizes human LAG-3. Isotype: Mouse IgG1. Clone: 17B4. Applications: FACS, FUNC (Blocking), ICC, IHC, IP, WB. Liquid. In PBS. Lymphocyte activation gene 3 (LAG-3, CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4.

Lymphocyte activation gene 3 (LAG-3, CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4.

Aufreinigung: Puified

Reinheit: >95 % (SDS-PAGE)

Endotoxin-Niveau: <0.001EU/μg purified protein or <1EU/mg purified protein (LAL test, Lonza).

Immunogen: Synthetic peptide corresponding to 30 aa in the N-terminus of human LAG-3.

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: In PBS.

Konservierungsmittel: Without preservative

Handhabung: After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung:

+4°C

Stable for at least 1 year after receipt when stored at -20°C.

Details zu LAG3

Target: LAG3 (Lymphocyte-Activation Gene 3 (LAG3))

Andere Bezeichnung: LAG-3

UniProt: P18627

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints