APAF1 Antikörper (AA 1201-1248)
Kurzübersicht für APAF1 Antikörper (AA 1201-1248) (ABIN724295)
Target
Alle APAF1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1201-1248
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Kreuzreaktivität
- Human, Ratte, Zebrafisch (Danio rerio)
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Homologie
- Mouse,Dog,Horse
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human Apaf-1
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Isotyp
- IgG
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Applikationshinweise
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Haltbarkeit
- 12 months
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Human interleukin 23 receptor induces cell apoptosis in mammalian cells by intrinsic mitochondrial pathway associated with the down-regulation of RAS/mitogen-activated protein kinase and signal ..." in: International journal of molecular sciences, Vol. 14, Issue 12, pp. 24656-69, (2014) (PubMed).
: "
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Human interleukin 23 receptor induces cell apoptosis in mammalian cells by intrinsic mitochondrial pathway associated with the down-regulation of RAS/mitogen-activated protein kinase and signal ..." in: International journal of molecular sciences, Vol. 14, Issue 12, pp. 24656-69, (2014) (PubMed).
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- APAF1 (Apoptotic Peptidase Activating Factor 1 (APAF1))
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Andere Bezeichnung
- APAF1CT
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Hintergrund
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Synonyms: CED4, APAF-1, Apoptotic protease-activating factor 1, APAF1, KIAA0413
Background: Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis.
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Gen-ID
- 317
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UniProt
- O14727
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Pathways
- p53 Signalweg, Apoptose, Caspase Kaskade in der Apoptose, Tube Formation, Positive Regulation of Endopeptidase Activity
Target
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