Choline Acetyltransferase Antikörper (AA 101-200)

Produktnummer ABIN724070

Der Kaninchen Polyklonal Anti-Choline Acetyltransferase-Antikörper wurde für ELISA, FACS, IF (cc), IF (p), IHC (p) und IHC (fro) validiert. Er ist geeignet, Choline Acetyltransferase in Proben von Human, Maus, Ratte und Hund zu detektieren. Es sind 4+ Publikationen verfügbar.

Kurzübersicht für Choline Acetyltransferase Antikörper (AA 101-200) (ABIN724070)

Target: Choline Acetyltransferase (CHAT) (Choline O-Acetyltransferase (CHAT))

Reaktivität: Human, Maus, Ratte, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Choline Acetyltransferase Antikörper ist unkonjugiert

Applikation: ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-Choline Acetyltransferase Antikörper

Bindungsspezifität: AA 101-200

Kreuzreaktivität: Hund, Human, Maus, Ratte

Homologie: Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ChAT

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-Choline Acetyltransferase Antikörper (ABIN724070)

Zhang, Zheng, Geng, Xue, Wang, Xie, Wang, Zhang, Hou: "MicroRNA profiling of atrial fibrillation in canines: miR-206 modulates intrinsic cardiac autonomic nerve remodeling by regulating SOD1." in: PLoS ONE, Vol. 10, Issue 3, pp. e0122674, (2015) (PubMed).

Wieck, El-Nachef, Hou, Spurrier, Holoyda, Schall, Garcia Mojica, Collins, Trecartin, Cheng, Frykman, Grikscheit: "Human and Murine Tissue-Engineered Colon Exhibit Diverse Neuronal Subtypes and Can Be Populated by Enteric Nervous System Progenitor Cells When Donor Colon Is Aganglionic." in: Tissue engineering. Part A, (2015) (PubMed).

Zhang, Jin, Li, Guan, Han, Zhang: "Catalpol improves cholinergic function and reduces inflammatory cytokines in the senescent mice induced by D-galactose." in: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, Vol. 58, pp. 50-5, (2013) (PubMed).

Zhu, Zhao, Luo, Li: "Gastrointestinal dysfunction in a Parkinson's disease rat model and the changes of dopaminergic, nitric oxidergic, and cholinergic neurotransmitters in myenteric plexus." in: Journal of molecular neuroscience : MN, Vol. 47, Issue 1, pp. 15-25, (2012) (PubMed).

Details zu Choline Acetyltransferase

Target: Choline Acetyltransferase (CHAT) (Choline O-Acetyltransferase (CHAT))

Andere Bezeichnung: ChAT

Hintergrund:

Synonyms: CMS1A, CMS1A2, CHOACTASE, Choline O-acetyltransferase, ChAT, Choline acetylase

Background: Catalyzes the reversible synthesis of acetylcholine (ACh) from acetyl CoA and choline at cholinergic synapses.

Gen-ID: 1103

UniProt: P28329

Pathways: Skeletal Muscle Fiber Development