Cytochrome C Antikörper (AA 51-105)
Kurzübersicht für Cytochrome C Antikörper (AA 51-105) (ABIN723590)
Target
Alle Cytochrome C (CYCS) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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                                            Bindungsspezifität
- AA 51-105
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                                            Kreuzreaktivität
- Huhn, Human, Maus, Kaninchen, Ratte
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                                            Homologie
- Cow,Pig,Horse,Guinea Pig
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                                            Aufreinigung
- Purified by Protein A.
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                                            Immunogen
- KLH conjugated synthetic peptide derived from human Cytochrome C
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                                            Isotyp
- IgG
 
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                                            Applikationshinweise
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                        WB 1:300-5000
 ELISA 1:500-1000
 FCM 1:20-100
 IHC-P 1:200-400
 IHC-F 1:100-500
 IF(IHC-P) 1:50-200
 IF(IHC-F) 1:50-200
 IF(ICC) 1:50-200
 ICC 1:100-500
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                                            Beschränkungen
- Nur für Forschungszwecke einsetzbar
 
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    - 
                                            Format
- Liquid
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                                            Konzentration
- 1 μg/μL
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                                            Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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                                            Konservierungsmittel
- ProClin
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                                            Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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                                            Lagerung
- 4 °C,-20 °C
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                                            Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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                                            Haltbarkeit
- 12 months
 
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    - 
                                            : "GluR3B Ab's induced oligodendrocyte precursor cells excitotoxicity via mitochondrial dysfunction."    in: Brain research bulletin, Vol. 130, pp. 60-66, (2017)         (PubMed).        
 : "Macrolide antibiotics differentially influence human HepG2 cytotoxicity and modulate intrinsic/extrinsic apoptotic pathways in rat hepatocellular carcinoma model." in: Naunyn-Schmiedeberg's archives of pharmacology, Vol. 390, Issue 4, pp. 379-395, (2017) (PubMed).
 : "Phosphoprotein Gene Contributes to the Enhanced Apoptosis Induced by Wild-Type Rabies Virus GD-SH-01 In Vitro." in: Frontiers in microbiology, Vol. 8, pp. 1697, (2017) (PubMed).
 : "ROS-mediated endoplasmic reticulum stress and mitochondrial dysfunction underlie apoptosis induced by resveratrol and arsenic trioxide in A549 cells." in: Chemico-biological interactions, Vol. 245, pp. 100-9, (2016) (PubMed).
 : "Antioxidant tert-butylhydroquinone ameliorates arsenic-induced intracellular damages and apoptosis through induction of Nrf2-dependent antioxidant responses as well as stabilization of anti-apoptotic ..." in: Free radical biology & medicine, Vol. 94, pp. 74-87, (2016) (PubMed).
 : "Sulfiredoxin-1 protects against simulated ischaemia/reperfusion injury in cardiomyocyte by inhibiting PI3K/AKT-regulated mitochondrial apoptotic pathways." in: Bioscience reports, Vol. 36, Issue 2, (2016) (PubMed).
 : "Resveratrol Synergistically Triggers Apoptotic Cell Death with Arsenic Trioxide via Oxidative Stress in Human Lung Adenocarcinoma A549 Cells." in: Biological trace element research, Vol. 163, Issue 1-2, pp. 112-23, (2015) (PubMed).
 : "Poly (ADP?ribose) polymerase? and cytochrome c?mediated apoptosis induces hepatocyte injury in a rat model of hyperammonia?induced hepatic failure." in: Molecular medicine reports, (2015) (PubMed).
 : "Increased Expression of Mitochondrial Inner-Membrane Protein Mpv17 After Intracerebral Hemorrhage in Adult Rats." in: Neurochemical research, Vol. 40, Issue 8, pp. 1620-30, (2015) (PubMed).
 : "Nuclear translocation of nuclear factor kappa B is regulated by G protein signaling pathway in arsenite-induced apoptosis in HBE cell line." in: Environmental toxicology, (2015) (PubMed).
 : "Millimeter Wave Treatment Inhibits Apoptosis of Chondrocytes via Regulation Dynamic Equilibrium of Intracellular Free Ca (2+)." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2015, pp. 464161, (2015) (PubMed).
 : "P62 regulates resveratrol-mediated Fas/Cav-1 complex formation and transition from autophagy to apoptosis." in: Oncotarget, Vol. 6, Issue 2, pp. 789-801, (2015) (PubMed).
 : "Guanabenz delays the onset of disease symptoms, extends lifespan, improves motor performance and attenuates motor neuron loss in the SOD1 G93A mouse model of amyotrophic lateral sclerosis." in: Neuroscience, Vol. 277, pp. 132-8, (2014) (PubMed).
 : "Resveratrol protects against arsenic trioxide-induced oxidative damage through maintenance of glutathione homeostasis and inhibition of apoptotic progression." in: Environmental and molecular mutagenesis, (2014) (PubMed).
 : "Evodiamine induces G2/M arrest and apoptosis via mitochondrial and endoplasmic reticulum pathways in H446 and H1688 human small-cell lung cancer cells." in: PLoS ONE, Vol. 9, Issue 12, pp. e115204, (2014) (PubMed).
 : "Organellar proteome analyses of ricin toxin-treated HeLa cells." in: Toxicology and industrial health, (2014) (PubMed).
 : "Mu-calpain mediates hippocampal neuron death in rats after lithium-pilocarpine-induced status epilepticus." in: Brain research bulletin, Vol. 76, Issue 1-2, pp. 90-6, (2008) (PubMed).
 
 
- 
                                            : "GluR3B Ab's induced oligodendrocyte precursor cells excitotoxicity via mitochondrial dysfunction."    in: Brain research bulletin, Vol. 130, pp. 60-66, (2017)         (PubMed).        
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    - Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))
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                                            Andere Bezeichnung
- Cytochrome C
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                                            Hintergrund
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                        Synonyms: CYC, HCS, THC4, Cytochrome c, CYCS Background: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases. 
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                                            Gen-ID
- 54205
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                                            UniProt
- P99999
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                                            Pathways
- Apoptose, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity
 Target
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