Metronidazole Antikörper (HRP)

Produktnummer ABIN723180

Produktdetails

Target: Metronidazole

Reaktivität: Chemical

Wirt: Maus

Klonalität: Monoklonal

Konjugat: HRP

Applikation: ELISA

Aufreinigung: Purified by Protein G.

Immunogen: KLH conjugated with Metronidazole

Klon: 1C2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.

Konservierungsmittel: Gentamicin sulfate

Vorsichtsmaßnahmen: This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 4°C

Haltbarkeit: 12 months

Antigendetails

Target: Metronidazole

Substanzklasse: Chemical

Hintergrund:

Metronidazole is a nitroimidazole antibiotic medication used particularly for anaerobic bacteria and protozoa. Metronidazole is an antibiotic, amebicide, and antiprotozoal.Metronidazole, taken up by diffusion, is selectively absorbed by anaerobic bacteria and sensitive protozoa. Once taken up by anaerobes, it is non-enzymatically reduced by reacting with reduced ferredoxin, which is generated by pyruvate oxido-reductase. Many of the reduced nitroso intermediates will form sulfinamides and thioether linkages with cysteine-bearing enzymes, thereby deactivating these critical enzymes. As many as 150 separate enzymes are affected.In addition or alternatively, the metronidazole metabolites are taken up into bacterial DNA, and form unstable molecules. This function only occurs when metronidazole is partially reduced, and because this reduction usually happens only in anaerobic cells, it has relatively little effect upon human cells or aerobic bacteria.

Synonyms: 2-Methyl-5-nitroimidazole-1-ethanol