Metronidazole Antikörper

Produktnummer ABIN723171

Der Maus Monoklonal anti-Metronidazole Antikörper (Klon 1C2) (ABIN723171) detektiert spezifisch Metronidazole in IHC (p) und IF (p). Dieser Antikörper reagiert spezifisch mit Proben aus Chemical.

Kurzübersicht für Metronidazole Antikörper (ABIN723171)

Target: Metronidazole

Reaktivität: Chemical

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Klon: 1C2

Produktdetails

Aufreinigung: Purified by Protein G.

Immunogen: KLH conjugated with Metronidazole

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P 1:100-500
IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C

Haltbarkeit: 12 months

Antigendetails

Target: Metronidazole

Substanzklasse: Chemical

Hintergrund:

Metronidazole is a nitroimidazole antibiotic medication used particularly for anaerobic bacteria and protozoa. Metronidazole is an antibiotic, amebicide, and antiprotozoal.Metronidazole, taken up by diffusion, is selectively absorbed by anaerobic bacteria and sensitive protozoa. Once taken up by anaerobes, it is non-enzymatically reduced by reacting with reduced ferredoxin, which is generated by pyruvate oxido-reductase. Many of the reduced nitroso intermediates will form sulfinamides and thioether linkages with cysteine-bearing enzymes, thereby deactivating these critical enzymes. As many as 150 separate enzymes are affected.In addition or alternatively, the metronidazole metabolites are taken up into bacterial DNA, and form unstable molecules. This function only occurs when metronidazole is partially reduced, and because this reduction usually happens only in anaerobic cells, it has relatively little effect upon human cells or aerobic bacteria.

Synonyms: 2-Methyl-5-nitroimidazole-1-ethanol