Rekombinanter Progesterone Receptor Antikörper

Produktnummer ABIN7543415

Dieses Maus Chimeric-Antikörper erkennt spezifisch Progesterone Receptor in WB, IHC und ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Rekombinanter Progesterone Receptor Antikörper (ABIN7543415)

Target: Progesterone Receptor (PGR)

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Maus

Klonalität: Chimeric

Konjugat: Dieser Progesterone Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Klon: 14B3

Produktdetails anti-Progesterone Receptor Antikörper

Verwendungszweck: Anti-Progesterone Receptor [14B3], Mouse IgG1, kappa

Spezifität: The antibody is specific for PR protein. PR is a protein molecule, a cellular core receptor belonging to a steroidal superfamily, which can be bonded to the corresponding hormone to form a hormone-receptor complex, enabling hormones to exert their biological effects.

Produktmerkmale:

Original Species of Ab: Rabbit

Original Format of Ab: IgG

Aufreinigung: Protein A affinity purified

Immunogen: The original antibody was generated by immunizing rabbits with PR protein.

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: The specificity of the original format of the antibody was confirmed by ELISA analysis (affinity constant of 1.82 x 10^10 M-1). The antibody specifically detected PR protein in Western blot analysis. The antibody 14B3 and the commercial antibody 1E2 were used to stain breast cancer and endometrial. Results showed the antibody specificity is comparable to the commercial antibody. Further, the sensitivity of the antibody 14B3 was higher than the commercial antibody (CN113583132A).

Kommentare:

This chimeric mouse antibody was made using the variable domain sequences of the original Rabbit IgG format for improved compatibility with existing reagents assays and techniques.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Details zu Progesterone Receptor

Target: Progesterone Receptor (PGR)

Andere Bezeichnung: Progesterone Receptor

Hintergrund: PR, Nuclear receptor subfamily 3 group C member 3

UniProt: P06401

Pathways: Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration