Rekombinanter TdT Antikörper

Produktnummer ABIN7543411

Dieses Anti-TdT-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von TdT in WB, ELISA und IHC. Geeignet für Human.

Kurzübersicht für Rekombinanter TdT Antikörper (ABIN7543411)

Target: TdT (DNTT) (Deoxynucleotidyltransferase, terminal (DNTT))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TdT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Klon: 32D5

Produktdetails anti-TdT Antikörper

Verwendungszweck: Anti-Terminal Deoxynucleotidyl Transferase [32D5], Mouse IgG2a, kappa

Spezifität: The antibody is specific for TdT. TdT catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator. One of the in vivo functions of this enzyme is the addition of nucleotides at the junction (N region) of rearranged Ig heavy chain and T-cell receptor gene segments during the maturation of B- and T-cells.

Produktmerkmale:

Original Species of Ab: Mouse

Original Format of Ab: IgG2a

Aufreinigung: Protein A affinity purified

Immunogen: The original antibody was generated by immunizing mice with the recombinant TdT protein.

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise: The antibody specifically detected TDT protein in Western blot analysis. The antibody 32D5 and the commercial antibody SEN28 were used to stain lymphoma and thymus. Results showed the antibody specificity is comparable to the commercial antibody. Further, the sensitivity of the antibody 32D5 was higher than the commercial antibody. The antibody and the commercially available antibody TA347 were simultaneously detected on the normal tissue chip, indicating that the specificity of the antibody in normal tissue was equivalent to that of the commercially available antibody (CN113265003A).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Details zu TdT

Target: TdT (DNTT) (Deoxynucleotidyltransferase, terminal (DNTT))

Andere Bezeichnung: Terminal Deoxynucleotidyl Transferase

Hintergrund: TdT, DNA nucleotidylexotransferase, Terminal addition enzyme, Terminal deoxynucleotidyltransferase, Terminal transferase, CGMCC NO 20777

UniProt: P04053

Pathways: DNA Reparatur