Rekombinanter LAG3 Antikörper

Produktnummer ABIN7543410

Der Kaninchen-Chimeric Anti-LAG3-Antikörper wurde für WB, ELISA und IHC validiert. Er ist geeignet zum Nachweis von LAG3 in Proben aus Human. }

Kurzübersicht für Rekombinanter LAG3 Antikörper (ABIN7543410)

Target: LAG3 (Lymphocyte-Activation Gene 3 (LAG3))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Chimeric

Konjugat: Dieser LAG3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Klon: 22G3

Produktdetails anti-LAG3 Antikörper

Verwendungszweck: Anti-LAG-3 [22G3], Rabbit IgG, kappa

Spezifität: The antibody is specific for LAG3. Lymphocyte activation gene 3 protein is an inhibitory receptor on antigen activated T-cells. It delivers inhibitory signals upon binding to ligands, such as FGL1.

Produktmerkmale:

Original Species of Ab: Mouse

Original Format of Ab: IgG2a

Aufreinigung: Protein A affinity purified

Immunogen: The original antibody was generated by immunizing mice with recombinant LAG3 protein.

Isotyp: IgG kappa

Anwendungsinformationen

Applikationshinweise: The antibody specifically detected LAG3 protein in Western blot analysis. The antibody and the commercial antibody EPR20261 were used to stain tonsillar granulocytes and granulocytes in the appendix. Results showed the antibody specificity is comparable to the commercial antibody. Further, the sensitivity of the antibody 22G3 was higher than the commercial antibody. The antibody and the commercially available antibody E3 were simultaneously detected on the normal tissue chip, indicating that the specificity of the antibody in normal tissue was equivalent to that of the commercially available antibody (CN113234159A).

Kommentare:

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2a format for improved compatibility with existing reagents assays and techniques.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Details zu LAG3

Target: LAG3 (Lymphocyte-Activation Gene 3 (LAG3))

Andere Bezeichnung: LAG-3

Hintergrund: CD223, LAG3, Lymphocyte-activation gene-3, Lymphocyte activation gene 3 protein, LAG-3, CGMCNO 20774

UniProt: P18627

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints