Rekombinanter MUC16 Antikörper
Kurzübersicht für Rekombinanter MUC16 Antikörper (ABIN7543399)
Target
Alle MUC16 (CA125) Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Anti-CA125 [20E3], Rabbit IgG, kappa
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Spezifität
- The original antibody is specific for CA125. CA125 is thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. This antigen that is the basis for a widely used serum assay for the monitoring of patients with ovarian epithelial cancer.
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Produktmerkmale
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Original Species of Ab: Mouse
Original Format of Ab: IgG2b
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Aufreinigung
- Protein A affinity purified
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Immunogen
- The original antibody was generated by immunizing mice with recombinant protein CA125.
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Isotyp
- IgG kappa
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Applikationshinweise
- The antibody 20E3 and the commercial antibody TA347 were used to stain ovarian slurry adenocarcinoma and ovarian mucous adenocarcinoma in immunohistochemistry. Results showed the antibody specificity is comparable to the commercial antibody. Further, the staining intensity of the antibody 20E3 was higher than the commercial antibody (CN113061186A).
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Kommentare
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This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2b format for improved compatibility with existing reagents assays and techniques.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % Proclin 300.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- MUC16 (CA125) (Mucin 16, Cell Surface Associated (CA125))
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Andere Bezeichnung
- CA125
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Hintergrund
- TA347, Mucin-16, MUC-16, Ovarian cancer-related tumor marker CA125, CA-125, Ovarian carcinoma antigen CA125, CGMCC NO 20773
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UniProt
- Q8WXI7
Target
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