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Rekombinanter PSMA Antikörper

Dieses Kaninchen Chimeric-Antikörper erkennt spezifisch PSMA in IHC und ELISA. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN7543286

Kurzübersicht für Rekombinanter PSMA Antikörper (ABIN7543286)

Target

Alle PSMA (FOLH1) Antikörper anzeigen
PSMA (FOLH1) (Folate Hydrolase (Prostate-Specific Membrane Antigen) 1 (FOLH1))

Antikörpertyp

Recombinant Antibody

Reaktivität

  • 135
  • 11
  • 8
  • 5
  • 5
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
Human

Wirt

  • 83
  • 55
  • 1
  • 1
Kaninchen

Klonalität

  • 101
  • 37
  • 2
Chimeric

Konjugat

  • 78
  • 9
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser PSMA Antikörper ist unkonjugiert

Applikation

  • 75
  • 72
  • 38
  • 30
  • 18
  • 15
  • 11
  • 11
  • 10
  • 5
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Immunohistochemistry (IHC), ELISA

Klon

11d1e5E10
  • Verwendungszweck

    Anti-PSMA [11d1e5E10], Rabbit IgG, kappa

    Spezifität

    This antibody binds an epitope between amino acids 370 and 750 of the human PSMA. Prostate-specific membrane antigen (PSMA) is a type II integral membrane glycoprotein belonging to the M28 peptidase family. It acts as a glutamate carboxypeptidase on different alternative substrate. It is highly expressed in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer.

    Produktmerkmale

    Original Species of Ab: Mouse

    Original Format of Ab: IgG1

    Aufreinigung

    Protein A affinity purified

    Immunogen

    The original antibody was generated by immunizing mice with a HIS tagged human PSMA fragment (amino acids between 307 to 750).

    Isotyp

    IgG kappa
  • Applikationshinweise

    The binding characterization of this antibody was done using ELISA. This antibody is also recommended for the detection of PSMA using immunohistochemistry (CN112480260).

    Kommentare

    This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format for improved compatibility with existing reagents assays and techniques.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    1 mg/mL

    Buffer

    PBS with 0.02 % Proclin 300.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • Target

    PSMA (FOLH1) (Folate Hydrolase (Prostate-Specific Membrane Antigen) 1 (FOLH1))

    Andere Bezeichnung

    PSMA

    Hintergrund

    PSM, FOLH1, FOLH, FGCP, GCPII, mGCP, NAALAD1, GIG27, Prostate specific membrane antigen, Glutamate carboxypeptidase 2, Cell growth-inhibiting gene 27 protein, Folate hydrolase 1, Folylpoly-gamma-glutamate carboxypeptidase, Glutamate carboxypeptidase II, Membrane glutamate carboxypeptidase, N-acetylated-alpha-linked acidic dipeptidase I, NAALADase I, Prostate-specific membrane antigen, Pteroylpoly-gamma-glutamate carboxypeptidase

    UniProt

    Q04609
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