Rekombinanter MBP Antikörper (AA 1-9)
Kurzübersicht für Rekombinanter MBP Antikörper (AA 1-9) (ABIN7543255)
Target
Alle MBP Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 1-9
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Verwendungszweck
- Anti-Myelin basic protein [F28C4], Mouse IgG2a, lambda
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Spezifität
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This antibody binds human myelin basic protein (MBP), acetyl residues 1-9 (ASQKRPSQR). The MBP isoforms 4 and 14 along with PLP are most abundant protein components of the myelin membrane in the CNS. The smaller isoforms are believed to have an important role in remyelination of denuded axons in multiple sclerosis.
Application Notes original Clone: This antibody shares a cross reactive idiotpe with the TCRs, possibly as a result of having similar fine epitope specificity and sequence homology (PMID: 7517973). This antibody can be used for the detection of MBP in a solution using ELISA (PMID: 8567971).
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Aufreinigung
- Protein A affinity purified
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Immunogen
- The original antibody was generated by immunizing PL/J mice with MBP acetyl residues 1-9.
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Isotyp
- IgG2a, lambda
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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OriginalSpeciesName: Mouse
OriginalFormat: IgG2a
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % Proclin 300.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- MBP (Myelin Basic Protein (MBP))
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Andere Bezeichnung
- Myelin basic protein
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Hintergrund
- MBP, Myelin A1 protein, Myelin membrane encephalitogenic protein
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UniProt
- P02686
Target
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