Rekombinanter TCR beta Antikörper
Kurzübersicht für Rekombinanter TCR beta Antikörper (ABIN7543083)
Target
Alle TCR beta Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Anti-TCR beta [IARC307], Rabbit IgG, kappa
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Spezifität
- This antibody is specific for Vbeta8.1 CDR1 sequence CKPISGHNSLFQWYRQT.
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Produktmerkmale
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Original Species of Ab: Human
Original Format of Ab: IgM
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Aufreinigung
- Protein A affinity purified
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Immunogen
- Derived from normal B cells in peripheral blood of a Burkitt's lymphoma patient. Screened more than 60 culture supernatants from lymphoblastoid cell lines of normal origin, Epstein-Barr virus (EBV)-carrying Burkitt lymphomas, EBV-negative Burkitt lymphomas and EBV-converted sublines of original EBV-negative Burkitt lymphoma human B-cell lines for their capacity to bind the synthetic peptide autoantigens. One lymphoblastoid B-cell line was identified, IARC307, that produces IgM kappa antibodies which specifically react with the CDR1 peptide corresponding to human Vbeta8.1 gene sequence.
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Isotyp
- IgG kappa
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Applikationshinweise
- IARC307 has been used in ELISAs to bind to synthetic peptides of CRD1 region from several TCR Vbeta families of man and mouse (Marchalonis 2000).
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Kommentare
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This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgM format, for improved compatibility with existing reagents, assays and techniques.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % Proclin 300.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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