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TCR beta Antikörper (APC)

TCR beta Reaktivität: Maus FACS Wirt: Armenischer Hamster Monoclonal H57-597 APC
Produktnummer ABIN7278032
  • Target Alle TCR beta Antikörper anzeigen
    TCR beta (T Cell Receptor (TCR) beta (TCR beta))
    Reaktivität
    • 44
    • 15
    Maus
    Wirt
    • 24
    • 20
    • 11
    • 4
    Armenischer Hamster
    Klonalität
    • 48
    • 11
    Monoklonal
    Konjugat
    • 16
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TCR beta Antikörper ist konjugiert mit APC
    Applikation
    • 47
    • 15
    • 10
    • 8
    • 8
    • 7
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Aufreinigung
    This monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation. It is recommended to store the product undiluted at 4°C, and protected from prolonged exposure to light. Do not freeze.
    Klon
    H57-597
    Isotyp
    IgG
    Top Product
    Discover our top product TCR beta Primärantikörper
  • Applikationshinweise
    This antibody preparation has been quality-tested for flow cytometry using mouse spleen cells, or an appropriate cell type (where indi- cated). The amount of antibody required for optimal staining of a cell sample should be determined empirically in your system.
    Kommentare

    0.2 mg/mL

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    10 mM NaH2PO4, 150 mM NaCl, 0.09 % Sodium azide, 0.1 % gelatin, pH 7.2
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    2-8°C protected from light
    Haltbarkeit
    12 months
  • Target
    TCR beta (T Cell Receptor (TCR) beta (TCR beta))
    Andere Bezeichnung
    TCR beta (TCR beta Produkte)
    Synonyme
    TCRbeta antikoerper, Tib antikoerper, T cell receptor beta chain antikoerper, Tcrb antikoerper
    Hintergrund
    The H57-597 antibody is specific for the beta chain of the mouse T cell Receptor (TCR). This cell surface protein combines with a second protein chain (alpha chain) to form the alpha-beta TCR that is expressed by NK1.1+ thymocytes, NKT cells, and the majority of peripheral T cells. A small number of T cells may express an alternative heteromer of gamma and delta protein chains, known as the gamma-delta TCR. These receptors participate in a complex with CD3, and with the co-receptors CD4 or CD8, to recognize and respond to antigens bound to MHC molecules on antigen-presenting cells. Such interactions promote T cell receptor signaling (T cell activation) and can re- sult in a number of cellular responses including proliferation, differentiation, production of cytokines or activation-induced cell death. The H57-597 antibody is used as a phenotypic marker for T cells expressing the alpha-beta TCR. It is also widely used to cross-link surface TCR and thereby mimic TCR-mediated cell activation or induction of apoptosis. The antibody does not cross-react with cells expressing the gamma-delta TCR.
    Gen-ID
    21577
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