Rekombinanter CD2 Antikörper
Kurzübersicht für Rekombinanter CD2 Antikörper (ABIN7543003)
Target
Alle CD2 Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Anti-CD2 [OX-34], Rabbit IgG, kappa
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Spezifität
- OX-34 binds specifically to rat CD2. CD2 is type I membrane protein involved in triggering of T-cells (cytoplasmic domain is involved in signaling function) and is expressed on thymocytes, peripheral T cells, dendritic epidermal T cells, macrophages in the spleen, and NK cells.
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Produktmerkmale
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Original Species of Ab: Mouse
Original Format of Ab: IgG2a
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Aufreinigung
- Protein A affinity purified
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Immunogen
- OX-34 was prepared by immunizing mice with T blasts prepared in mixed lymphocyte reactions with purified rat T helper cells against irradiated spleen.
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Isotyp
- IgG kappa
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Applikationshinweise
- Ox34 blocks CD48 binding to CD2 causing partial block of T cell activation, OX34 can be used to deplete peripheral T cells (used to prevent allograft rejection in vivo).
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Kommentare
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This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % Proclin 300.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- CD2
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Andere Bezeichnung
- CD2
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Hintergrund
- LFA-2, LFA2, OX-34 antigen, OX34 antigen, T-cell surface antigen T11/Leu5, T cell surface antigen T11/Leu5, OX34, MRC OX34, MRC OX-34
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UniProt
- P08921
Target
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