Rekombinanter Transferrin Receptor Antikörper

Produktnummer ABIN7543001

Dieses Kaninchen Chimeric-Antikörper erkennt spezifisch Transferrin Receptor in FACS, WB, IF, IHC (fro) und in vivo. Er zeigt eine Reaktivität gegenüber Ratte.

Kurzübersicht für Rekombinanter Transferrin Receptor Antikörper (ABIN7543001)

Target: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Antikörpertyp: Recombinant Antibody

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Chimeric

Konjugat: Dieser Transferrin Receptor Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), In vivo Studies (in vivo)

Klon: OX-26

Produktdetails anti-Transferrin Receptor Antikörper

Verwendungszweck: Anti-CD71 [OX-26], Rabbit IgG, kappa

Spezifität: This antibody binds to rat CD71, the transferrin recepetor.

Produktmerkmale:

Original Species of Ab: Mouse

Original Format of Ab: IgG2a

Aufreinigung: Protein A affinity purified

Immunogen: OX-26 was prepared by immunizing BALB/c mice with rat transferrin receptor.

Isotyp: IgG kappa

Anwendungsinformationen

Applikationshinweise: This antibody binds to the rat transferrin receptor, and in its original mouse IgG2a version, it was shown to be taken up into the brain across the blood-brain barrier (Moss 2001). Mutational screening showed that this process is dependent on the antibody's affinity for its target (Haqqani 2018). The antibody can also be used in flow cytometry, immunofluorescence, and western blot, and it may also be used in frozen-section IHC.

Kommentare:

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Details zu Transferrin Receptor

Target: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Andere Bezeichnung: CD71

Hintergrund: Transferrin receptor, TfR, p90, T9, TFR1, OX26, MRC OX26, MRC OX-26

UniProt: Q99376

Pathways: Transition Metal Ion Homeostasis