Rekombinanter MHC Class II Antikörper

Produktnummer ABIN7542975

Der Kaninchen Chimeric Anti-MHC Class II-Antikörper wurde für FACS, WB, IHC, IP, IF, RIA und ICC validiert. Er ist geeignet, MHC Class II in Proben von Ratte zu detektieren.

Kurzübersicht für Rekombinanter MHC Class II Antikörper (ABIN7542975)

Target: MHC Class II (MHC2) (Major Histocompatibility Complex Class II Antigen (MHC2))

Antikörpertyp: Recombinant Antibody

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Chimeric

Konjugat: Dieser MHC Class II Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF), Radioimmunoassay (RIA), Immunocytochemistry (ICC)

Klon: OX-6

Produktdetails anti-MHC Class II Antikörper

Verwendungszweck: Anti-MHC II [OX-6], Rabbit IgG, kappa

Spezifität: This antibody recognises a monomorphic determinant of the rat MHC II (I-A) antigen present on B lymphocytes, dendritic cells, some macrophages and certain epithelial cells. It also cross-reacts with mouse MHC, specifically I-A[k] and I-A[s]

Kreuzreaktivität: Maus

Produktmerkmale:

Original Species of Ab: Mouse

Original Format of Ab: IgG1

Aufreinigung: Protein A affinity purified

Immunogen: This antibody was prepared by subcutaneously injecting non-polymorphic MHC class II (Ia-like glycoproteins) from the membranes of rat thymocytes into BALB/c mice.

Isotyp: IgG kappa

Anwendungsinformationen

Applikationshinweise: This antibody binds to the rat MHC II (I-A) antigen, and cross-reacts with mouse I-A[k] and I-A[s]. Consequently, this antibody can be used to assess the tissue distribution of rat Ia antigens, indicating high Ia antigen expression on peripheral B lymphocytes, and significantly lower expression on thymocytes and T lymphocytes (McMaster, 1979).

Kommentare:

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Details zu MHC Class II

Target: MHC Class II (MHC2) (Major Histocompatibility Complex Class II Antigen (MHC2))

Andere Bezeichnung: MHC II

Hintergrund: MHC Class II, MRC OX-6, CD74, MRC OX 6, Major Histocompatibility complex II