ADRB1 Antikörper (Internal Region)

Produktnummer ABIN7540608

Hersteller Produkt- Nr.: 600-401-mh1s

Der Kaninchen Polyklonal Anti-ADRB1-Antikörper wurde für WB, ELISA und FACS validiert. Er ist geeignet, ADRB1 in Proben von Human zu detektieren.

Kurzübersicht für ADRB1 Antikörper (Internal Region) (ABIN7540608)

Target: ADRB1 (Adrenergic, beta-1-, Receptor (ADRB1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ADRB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Produktdetails anti-ADRB1 Antikörper

Bindungsspezifität: Internal Region

Hersteller Produkt- Nr.: 600-401-mh1s

Hersteller: Rockland

Verwendungszweck: BETA 1 ADRENERGIC RECEPTOR Antibody

Kreuzreaktivität (Details): This affinity purified antibody is directed against human beta 1 adrenergic.

Aufreinigung: The antibody was affinity purified from monospecific antiserum by immunoaffinity purification.

Sterilität: Sterile filtered

Immunogen: Anti-Beta 1 Adrenergic Receptor (RABBIT) Antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal portion of human beta 1 adrenergic conjugated to Keyhole Limpet Hemocyanin (KLH).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

ELISA_Dilution: 1:10,000-1:15,000

Flow_Cytometry_Dilution: 1:20

Western_Blot_Dilution: 1:1000

Kommentare:

Suggested Applications: User Optimized
Anti-Beta 1 Adrenergic Receptor Antibody has been tested in ELISA, WB, and FLOW. Expect a band at ~51kDa in western blot using appropriate lysates. Positive control used: human heart muscle membrane tissues in WB and NCCIT cells in FLOW. Although not tested, this antibody may be suitable in IHC.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: None

Preservative: 0.01 % (w/v) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store vial at -20° C or below prior to opening. This vial contains a relatively low volume of reagent (25 μL). To minimize loss of volume dilute 1:10 by adding 225 μL of the buffer stated above directly to the vial. Recap, mix thoroughly and briefly centrifuge to collect the volume at the bottom of the vial. Use this intermediate dilution when calculating final dilutions as recommended below. Store the vial at -20°C or below after dilution. Avoid cycles of freezing and thawing.

Haltbarkeit: 12 months

Details zu ADRB1

Target: ADRB1 (Adrenergic, beta-1-, Receptor (ADRB1))

Andere Bezeichnung: ADRB1

Hintergrund: Rabbit Anti-Beta-1 Adrenergic receptor Antibody, Rabbit Anti-Adrenergic ß1R Antibody, Adrenoceptor Beta 1, Adrenergic Beta-1-Receptor, Beta-1 Adrenoreceptor, Beta-1 Adrenoceptor, Adrb1r, B1AR, Beta-1 Adrenergic Receptor, BETA1AR, RHR, Beta-1 adrenergic receptor,The adrenergic beta1 receptor (beta1-adrenoceptor) is a member of the adrenergic receptor group of G-protein-coupled receptors that also includes alpha1A, alpha1B, alpha1D, alpha2A, alpha2B, alpha2C, beta2 and beta3. They are located primarily in the CNS, heart, coronary artery, kidney and muscle. Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity. Mediates Ras activation through G(s)-alpha- and cAMP-mediated signaling. Specific polymorphisms in this gene have been shown to affect the resting heart rate and can be involved in heart failure. Anti-Beta 1 Adrenergic Receptor Antibody is useful for researchers interested in cardiac function and G-protein signaling pathways.

Gen-ID: 153

NCBI Accession: NP_000675

UniProt: P08588

Pathways: cAMP Metabolic Process, Cellular Glucan Metabolic Process, Regulation of Muscle Cell Differentiation, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Brown Fat Cell Differentiation