CD70 Antikörper (FITC)

Produktnummer ABIN7540451

Dieser Maus Monoklonal Antikörper erkennt spezifisch CD70 in FACS. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CD70 Antikörper (FITC) (ABIN7540451)

Target: CD70 (CD70 Molecule (CD70))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD70 Antikörper ist konjugiert mit FITC

Applikation: Flow Cytometry (FACS)

Klon: Ki-24

Produktdetails anti-CD70 Antikörper (FITC)

Verwendungszweck: Anti-Hu CD70 FITC

Spezifität: The mouse monoclonal antibody Ki-24 recognizes an extracellular epitope of CD70, an approximately 50 kDa type II transmembrane glycoprotein expressed on activated lymphocytes and some B cell leukemias.

Aufreinigung: Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogen: human L428 cell line

Isotyp: IgG3 kappa

Anwendungsinformationen

Applikationshinweise: Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Details zu CD70

Target: CD70 (CD70 Molecule (CD70))

Andere Bezeichnung: CD70

Hintergrund:

NCBI Full Gene Name: CD70 Molecule

Description: CD70, also known as TNFSF7 or CD27L, is a 50 kDa type II transmembrane glycoprotein of the TNF superfamily. It is expressed mainly on activated lymphocytes, including NK cells, and forms trimeric structure. CD70 plays a role in T-cell activation, proliferation and differentiation, in enhancing the generation of cytolytic T cells, and in long-term maintenance of T cell memory. It is also involved in B cell differentiation induced by activated plasmacytoid dendritic cells, which also express CD70.

Other names: CD27L, TNFSF7, CD27 ligand, TNLG8A

Gene name: CD70

Gen-ID: 970

UniProt: P32970

Pathways: Cancer Immune Checkpoints