Rekombinanter CD31 Antikörper (Extracellular Domain) (Atto 565)

Produktnummer ABIN7540329

Dieses Alpaca Multiclonal-Antikörper erkennt spezifisch CD31 in IF, IF/ICC und IF (p). Er zeigt eine Reaktivität gegenüber Maus.

Kurzübersicht für Rekombinanter CD31 Antikörper (Extracellular Domain) (Atto 565) (ABIN7540329)

Target: CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))

Antikörpertyp: Recombinant Antibody

Fragment: single-domain Antibody (sdAb)

Reaktivität: Maus

Wirt: Alpaca

Klonalität: Multiclonal

Konjugat: Dieser CD31 Antikörper ist konjugiert mit Atto 565

Applikation: Immunofluorescence (IF), Immunofluorescence (fixed cells) (IF/ICC), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Klon: 3ELC120-3ELC140-3ELC105-3ELC143

Produktdetails anti-CD31 Antikörper (Atto 565)

Bindungsspezifität: Extracellular Domain

Expressionssystem: E.coli

Verwendungszweck: Alpaca anti-mouse CD31 VHH is a carefully developed and validated nanobody (single-domain antibody) binding to human CD31 (PECAM-1) highly suitabe for tissue staining.

Marke: LIMAAbody®

Spezifität: Detects endogenous levels of total murine CD31 protein.

Kreuzreaktivität (Details): not analysed

Produktmerkmale: VHH protein tag: C-terminal (6x) His-Tag

Aufreinigung: Affinity-purified antibody fragment.

Immunogen: Recombinant protein containing the extracellular domain of murine CD31 protein.

Anwendungsinformationen

Applikationshinweise: Immunofluorescence: 10 μg/mL (frozen sections), 1 μg/mL (cell culture), 20 μg/mL (wholemount)

Kommentare:

VHH protein tag: C-terminal (6x) His-Tag

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, pH 7.4, 0.02% sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Do not freeze.

Lagerung: 4 °C

Informationen zur Lagerung: Upon receipt store at 4°C. Stable for 6 months. Do not freeze.

Haltbarkeit: 6 months

Details zu CD31

Target: CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))

Andere Bezeichnung: CD31

Hintergrund: CD31, also known as PECAM-1, is an adhesion molecule and is expressed on endothelial cells at intercellular junctions and various T cell subsets. It shows altered expression levels in arterial, venous and lymphatic vessels. It is also found to a lesser extent on platelets, as well as most other leukocytes including monocytes and neutrophils. CD31 facilitates homotypic binding to itself, as well as heterotypic binding to the leukocyte integrin alpha V beta III. CD31 plays a crucial role in facilitating the transendothelial migration of leukocytes through the intercellular junctions of vascular endothelial cells. It is one of key regulatory molecules in vascular system.

Molekulargewicht: 81 kDa

NCBI Accession: NP_033868

UniProt: Q08481

Pathways: Regulation of Actin Filament Polymerization