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Rekombinanter CD31 Antikörper (Extracellular Domain)

Name: Rekombinanter CD31 Antikörper (Extracellular Domain)
SKU: ABIN7540328
Price: 415.77 EUR
Availability: InStock

PECAM1 Reaktivität: Maus IF, IF/ICC, IF (p) Wirt: Alpaca Multiclonal 3ELC120-3ELC140-3ELC105-3ELC143 unconjugated single-domain Antibody (sdAb) Recombinant Antibody

Immunofluorescence Staining of entire E10. (Rekombinanter CD31 Antikörper (Extracellular Domain))

Immunofluorescence analysis of mouse embryo frozen section using using CD31 (MEC13. (Rekombinanter CD31 Antikörper (Extracellular Domain))

4 Abbildungen

Produktnummer ABIN7540328

Datenblatt (PDF)

Target Alle CD31 (PECAM1) Antikörper anzeigen

CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))

Antikörpertyp

Recombinant Antibody

Fragment

single-domain Antibody (sdAb)
Bindungsspezifität
16

16

15

12

9

8

7

7

6

6

4

4

4

3

3

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Extracellular Domain
Reaktivität
270

148

75

59

44

31

21

20

11

7

4

4

4

1

1

1
Maus
Wirt
164

140

54

7

6

3

2
Alpaca

Expressionssystem

E.coli
Klonalität
241

127

7

1
Multiclonal
Konjugat
162

33

31

25

13

6

6

5

5

5

5

5

5

5

5

5

4

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1
Dieser CD31 Antikörper ist unkonjugiert
Applikation
240

180

105

101

63

39

37

33

33

26

21

15

12

12

9

6

4

3

3

2

2

2

2

1

1

1

1

1
Immunofluorescence (IF), Immunofluorescence (fixed cells) (IF/ICC), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Verwendungszweck

Alpaca anti-mouse CD31 VHH is a carefully developed and validated nanobody (single-domain antibody) binding to human CD31 (PECAM-1) highly suitabe for tissue staining.

Marke

LIMAAbody®

Spezifität

Detects endogenous levels of total murine CD31 protein.

Kreuzreaktivität (Details)

not analysed

Produktmerkmale

VHH protein tag: C-terminal (6x) His-Tag

Aufreinigung

Affinity-purified antibody fragment.

Immunogen

Recombinant protein containing the extracellular domain of murine CD31 protein.

Klon

3ELC120-3ELC140-3ELC105-3ELC143

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Applikationshinweise

Immunofluorescence: 10 μg/mL (frozen sections), 1 μg/mL (cell culture), 20 μg/mL (wholemount)

Kommentare

VHH protein tag: C-terminal (6x) His-Tag

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

1 mg/mL

Buffer

PBS, pH 7.4, 0.02% sodium azide

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung

Do not freeze.

Lagerung

4 °C

Informationen zur Lagerung

Upon receipt store at 4°C. Stable for 6 months. Do not freeze.

Haltbarkeit

6 months
Target

CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))

Andere Bezeichnung

CD31 (PECAM1 Produkte)

Hintergrund

CD31, also known as PECAM-1, is an adhesion molecule and is expressed on endothelial cells at intercellular junctions and various T cell subsets. It shows altered expression levels in arterial, venous and lymphatic vessels. It is also found to a lesser extent on platelets, as well as most other leukocytes including monocytes and neutrophils. CD31 facilitates homotypic binding to itself, as well as heterotypic binding to the leukocyte integrin alpha V beta III. CD31 plays a crucial role in facilitating the transendothelial migration of leukocytes through the intercellular junctions of vascular endothelial cells. It is one of key regulatory molecules in vascular system.

Molekulargewicht

81 kDa

NCBI Accession

NP_033868

UniProt

Q08481

Pathways

Regulation of Actin Filament Polymerization