Rekombinanter CD31 Antikörper (Extracellular Domain) (Atto 565)

Produktnummer ABIN7540325

Dieses Anti-CD31-Antikörper ist ein Alpaca Multiclonal-Antikörper zur Detektion von CD31 in IF, IF/ICC und IF (p). Geeignet für Human.

Kurzübersicht für Rekombinanter CD31 Antikörper (Extracellular Domain) (Atto 565) (ABIN7540325)

Target: CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))

Antikörpertyp: Recombinant Antibody

Fragment: single-domain Antibody (sdAb)

Reaktivität: Human

Wirt: Alpaca

Klonalität: Multiclonal

Konjugat: Dieser CD31 Antikörper ist konjugiert mit Atto 565

Applikation: Immunofluorescence (IF), Immunofluorescence (fixed cells) (IF/ICC), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Klon: 2MAC4-2PEC47-3MAC24-3MAC69-3MAC82-3PEC92

Produktdetails anti-CD31 Antikörper (Atto 565)

Bindungsspezifität: Extracellular Domain

Expressionssystem: E.coli

Verwendungszweck: Alpaca anti-human CD31 VHH is a carefully developed and validated nanobody (single-domain antibody) binding to human CD31 (PECAM-1) highly suitabe for tissue staining.

Marke: LIMAAbody®

Spezifität: Detects endogenous levels of total human CD31 protein.

Kreuzreaktivität (Details): does not cross-react with mouse CD31 based on qualitative analysis

Produktmerkmale: VHH protein tag: C-terminal (6x) His-Tag

Aufreinigung: Affinity-purified antibody fragment.

Immunogen: Recombinant protein containing the extracellular domain of murine CD31 protein.

Anwendungsinformationen

Applikationshinweise: Immunofluorescence: 10 μg/mL (frozen sections), 5 μg/mL (cell culture), 20 μg/mL (wholemount)

Kommentare:

VHH protein tag: C-terminal (6x) His-Tag

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, pH 7.4, 0.02% sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Do not freeze.

Lagerung: 4 °C

Informationen zur Lagerung: Upon receipt store at 4°C. Stable for 6 months. Do not freeze.

Haltbarkeit: 6 months

Details zu CD31

Target: CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))

Andere Bezeichnung: CD31

Hintergrund: CD31, also known as PECAM-1, is an adhesion molecule, which is expressed on endothelial cells at intercellular junctions and various T cell subsets. It is also found to be expressed on platelets, as well as most other leukocytes including monocytes and neutrophils. CD31 facilitates homotypic binding to itself, as well as heterotypic binding to the leukocyte integrins. CD31 plays a crucial role in facilitating the transendothelial migration of leukocytes through the intercellular junctions of vascular endothelial cells.

Molekulargewicht: 82 kDa

NCBI Accession: NP_000433

UniProt: P16284

Pathways: Regulation of Actin Filament Polymerization