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Rekombinanter CD31 Antikörper (Extracellular Domain)

Name: Rekombinanter CD31 Antikörper (Extracellular Domain)
SKU: ABIN7540324
Price: 848.01 EUR
Availability: InStock

PECAM1 Reaktivität: Human IF, IF/ICC, IF (p) Wirt: Alpaca Multiclonal 2MAC4-2PEC47-3MAC24-3MAC69-3MAC82-3PEC92 unconjugated single-domain Antibody (sdAb) Recombinant Antibody

Immunofluorescence analysis of human skin frozen section using CD31 (JC/70, 1. (Rekombinanter CD31 Antikörper (Extracellular Domain))

Immunofluorescence analysis of entire human skin, optically cleared with BABB, using CD31 (2MAC4, 2PEC47, 3MAC24, 3MAC69, 3MAC82, 3PEC82, 20 μg/mL) polyclonal LIMAAbody®, labelled with Alexa Fluor® 647 imaged on Zeiss LS7. (Rekombinanter CD31 Antikörper (Extracellular Domain))

2 Abbildungen

Produktnummer ABIN7540324

Datenblatt (PDF)

Target Alle CD31 (PECAM1) Antikörper anzeigen

CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))

Antikörpertyp

Recombinant Antibody

Fragment

single-domain Antibody (sdAb)
Bindungsspezifität
16

16

15

12

9

8

7

7

7

7

4

4

4

4

4

3

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Extracellular Domain
Reaktivität
279

154

78

62

44

31

21

20

11

7

4

4

4

1

1

1
Human
Wirt
168

155

54

7

6

3

2
Alpaca

Expressionssystem

E.coli
Klonalität
251

136

7

1
Multiclonal
Konjugat
179

33

33

25

13

6

6

5

5

5

5

5

5

5

5

5

4

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1
Dieser CD31 Antikörper ist unkonjugiert
Applikation
246

199

120

110

71

48

36

33

33

26

23

22

12

12

9

6

4

3

3

2

2

2

2

1

1

1

1

1
Immunofluorescence (IF), Immunofluorescence (fixed cells) (IF/ICC), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Verwendungszweck

Alpaca anti-human CD31 VHH is a carefully developed and validated nanobody (single-domain antibody) binding to human CD31 (PECAM-1) highly suitabe for tissue staining.

Marke

LIMAAbody®

Spezifität

Detects endogenous levels of total human CD31 protein.

Kreuzreaktivität (Details)

does not cross-react with mouse CD31 based on qualitative analysis

Produktmerkmale

VHH protein tag: C-terminal (6x) His-Tag

Aufreinigung

Affinity-purified antibody fragment.

Immunogen

Recombinant protein containing the extracellular domain of murine CD31 protein.

Klon

2MAC4-2PEC47-3MAC24-3MAC69-3MAC82-3PEC92

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Applikationshinweise

Immunofluorescence: 10 μg/mL (frozen sections), 5 μg/mL (cell culture), 20 μg/mL (wholemount)

Kommentare

VHH protein tag: C-terminal (6x) His-Tag

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

1 mg/mL

Buffer

PBS, pH 7.4, 0.02% sodium azide

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung

Do not freeze.

Lagerung

4 °C

Informationen zur Lagerung

Upon receipt store at 4°C. Stable for 6 months. Do not freeze.

Haltbarkeit

6 months
Target

CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))

Andere Bezeichnung

CD31 (PECAM1 Produkte)

Hintergrund

CD31, also known as PECAM-1, is an adhesion molecule, which is expressed on endothelial cells at intercellular junctions and various T cell subsets. It is also found to be expressed on platelets, as well as most other leukocytes including monocytes and neutrophils. CD31 facilitates homotypic binding to itself, as well as heterotypic binding to the leukocyte integrins. CD31 plays a crucial role in facilitating the transendothelial migration of leukocytes through the intercellular junctions of vascular endothelial cells.

Molekulargewicht

82 kDa

NCBI Accession

NP_000433

UniProt

P16284

Pathways

Regulation of Actin Filament Polymerization