MAP2K5 Antikörper (AA 63-180)

Produktnummer ABIN7539842

Der Maus Monoklonal anti-MAP2K5 Antikörper (Klon 5H11B10) (ABIN7539842) detektiert spezifisch MAP2K5 in WB, ELISA, IHC und FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für MAP2K5 Antikörper (AA 63-180) (ABIN7539842)

Target: MAP2K5 (Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MAP2K5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Klon: 5H11B10

Produktdetails anti-MAP2K5 Antikörper

Bindungsspezifität: AA 63-180

Verwendungszweck: MAP2K5 Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human MAP2K5 (AA: 63-180) expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Details zu MAP2K5

Target: MAP2K5 (Mitogen-Activated Protein Kinase Kinase 5 (MAP2K5))

Andere Bezeichnung: MAP2K5

Hintergrund: The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described.

Molekulargewicht: 50 kDa

UniProt: Q13163

Pathways: MAPK Signalweg, Neurotrophin Signalübertragung