Integrin beta 4 Antikörper (AA 1619-1822)

Produktnummer ABIN7539830

Dieses Anti-Integrin beta 4-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von Integrin beta 4 in IHC, FACS und ELISA. Geeignet für Human.

Kurzübersicht für Integrin beta 4 Antikörper (AA 1619-1822) (ABIN7539830)

Target: Integrin beta 4 (ITGB4)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Integrin beta 4 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Flow Cytometry (FACS), ELISA

Klon: 10B10D5

Produktdetails anti-Integrin beta 4 Antikörper

Bindungsspezifität: AA 1619-1822

Verwendungszweck: ITGB4 Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human ITGB4 (AA: 1619-1822) expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Details zu Integrin beta 4

Target: Integrin beta 4 (ITGB4)

Andere Bezeichnung: ITGB4

Hintergrund: Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Molekulargewicht: 202 kDa

Gen-ID: 3691

UniProt: P16144

Pathways: Integrin Complex