NOTCH4 Antikörper (AA 118-357)

Produktnummer ABIN7539818

Dieses Anti-NOTCH4-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von NOTCH4 in ELISA, IHC und FACS. Geeignet für Human.

Kurzübersicht für NOTCH4 Antikörper (AA 118-357) (ABIN7539818)

Target: NOTCH4 (Notch 4 (NOTCH4))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser NOTCH4 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Klon: 6D8D4

Produktdetails anti-NOTCH4 Antikörper

Bindungsspezifität: AA 118-357

Verwendungszweck: NOTCH4 Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human NOTCH4 (AA: 118-357) expressed in E. Coli.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Details zu NOTCH4

Target: NOTCH4 (Notch 4 (NOTCH4))

Andere Bezeichnung: NOTCH4

Hintergrund: This gene encodes a member of the NOTCH family of proteins. Members of this Type I transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple different domain types. Notch signaling is an evolutionarily conserved intercellular signaling pathway that regulates interactions between physically adjacent cells through binding of Notch family receptors to their cognate ligands. The encoded preproprotein is proteolytically processed in the trans-Golgi network to generate two polypeptide chains that heterodimerize to form the mature cell-surface receptor. This receptor may play a role in vascular, renal and hepatic development. Mutations in this gene may be associated with schizophrenia. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

Molekulargewicht: 209.6 kDa

Gen-ID: 4855

UniProt: Q99466

Pathways: Notch Signalweg