RAD23B Antikörper

Produktnummer ABIN7539777

Dieses Maus Monoklonal-Antikörper erkennt spezifisch RAD23B in WB, IHC, ICC und FACS. Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für RAD23B Antikörper (ABIN7539777)

Target: RAD23B (RAD23 Homolog B (RAD23B))

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser RAD23B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Klon: 6D2B3

Produktdetails anti-RAD23B Antikörper

Verwendungszweck: RAD23B Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human RAD23B expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

FCM: 1/200 - 1/400

ICC: 1/100 - 1/400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Details zu RAD23B

Target: RAD23B (RAD23 Homolog B (RAD23B))

Andere Bezeichnung: RAD23B

Hintergrund: The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER). This protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro. This protein was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus this protein may be involved in the ubiquitin mediated proteolytic pathway in cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Molekulargewicht: 43.2 kDa

Gen-ID: 5887

UniProt: P54727

Pathways: DNA Reparatur