SH2B2 Antikörper (AA 497-676)
Kurzübersicht für SH2B2 Antikörper (AA 497-676) (ABIN7539759)
Target
Alle SH2B2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 497-676
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Verwendungszweck
- SH2B2 Antibody
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Aufreinigung
- Purified antibody
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Immunogen
- Purified recombinant fragment of human SH2B2 (AA: 497-676) expressed in E. Coli.
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Isotyp
- IgG2b
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Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- SH2B2 (SH2B Adaptor Protein 2 (SH2B2))
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Andere Bezeichnung
- SH2B2
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Hintergrund
- The protein encoded by this gene is expressed in B lymphocytes and contains pleckstrin homology and src homology 2 (SH2) domains. In Burkitt's lymphoma cell lines, it is tyrosine-phosphorylated in response to B cell receptor stimulation. Because it binds Shc independent of stimulation and Grb2 after stimulation, it appears to play a role in signal transduction from the receptor to the Shc/Grb2 pathway.
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Molekulargewicht
- 67.7 kDa
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UniProt
- O14492
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Pathways
- Carbohydrate Homeostasis, Brown Fat Cell Differentiation
Target
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