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SH2B2 Antikörper (N-Term)

SH2B2 Reaktivität: Human, Ratte, Maus ELISA, WB, ICC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6256908
  • Target Alle SH2B2 Antikörper anzeigen
    SH2B2 (SH2B Adaptor Protein 2 (SH2B2))
    Bindungsspezifität
    N-Term
    Reaktivität
    Human, Ratte, Maus
    Wirt
    • 11
    Kaninchen
    Klonalität
    • 11
    Polyklonal
    Konjugat
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SH2B2 Antikörper ist unkonjugiert
    Applikation
    ELISA, Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
    Spezifität
    SH2B2 Antibody detects endogenous levels of total SH2B2.
    Homologie
    Pig,Zebrafish,Bovine,Horse,Rabbit,Dog,Chicken,Xenopus
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human SH2B2, corresponding to a region within N-terminal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product SH2B2 Primärantikörper
  • Applikationshinweise
    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    SH2B2 (SH2B Adaptor Protein 2 (SH2B2))
    Andere Bezeichnung
    SH2B2 (SH2B2 Produkte)
    Synonyme
    APS antikoerper, Aps antikoerper, SH2B adaptor protein 2 antikoerper, SH2B2 antikoerper, Sh2b2 antikoerper
    Hintergrund

    Description: Adapter protein for several members of the tyrosine kinase receptor family. Involved in multiple signaling pathways. May be involved in coupling from immunoreceptor to Ras signaling. Acts as a negative regulator of cytokine signaling in collaboration with CBL. Binds to EPOR and suppresses EPO-induced STAT5 activation, possibly through a masking effect on STAT5 docking sites in EPOR. Suppresses PDGF-induced mitogenesis. May induce cytoskeletal reorganization via interaction with VAV3.

    Gene: SH2B2

    Molekulargewicht
    67 kDa
    Gen-ID
    10603
    UniProt
    O14492
    Pathways
    Carbohydrate Homeostasis, Brown Fat Cell Differentiation
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