Cyclin B3 Antikörper (AA 142-363)
Kurzübersicht für Cyclin B3 Antikörper (AA 142-363) (ABIN7539697)
Target
Alle Cyclin B3 (CCNB3) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 142-363
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Verwendungszweck
- CCNB3 Antibody
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Aufreinigung
- Purified antibody
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Immunogen
- Purified recombinant fragment of human CCNB3 (AA: 142-363) expressed in E. Coli.
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Isotyp
- IgG1
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Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Cyclin B3 (CCNB3)
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Andere Bezeichnung
- CCNB3
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Hintergrund
- The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as positive regulators of cyclin-dependent kinases (CDKs), and thereby play an essential role in the control of the cell cycle. Different cyclins exhibit distinct expression and degradation patterns, which contribute to the temporal coordination of each mitotic event. Studies of similar genes in chicken and drosophila suggest that this cyclin may associate with CDC2 and CDK2 kinases, and may be required for proper spindle reorganization and restoration of the interphase nucleus. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
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Molekulargewicht
- 158 kDa
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Gen-ID
- 85417
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UniProt
- Q8WWL7
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Pathways
- Zellzyklus, Chromatin Binding
Target
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