TYRO3
Reaktivität: Human
ELISA
Wirt: Maus
Monoclonal
10E11
unconjugated
Applikationshinweise
ELISA: 1/10000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Buffer
Ascitic fluid containing 0.03 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Target
TYRO3
(TYRO3 Protein Tyrosine Kinase (TYRO3))
Andere Bezeichnung
Tyro3
Hintergrund
Tyro3 (also known as Sky and Rse), with 890-amino acid protein (about 98 kDa), belongs to the Axl/Tyro3 family of receptor tyrosine kinases, which also includes Axl and Mer.Gas6 (growth arrest-specific gene-6) is a ligand for all members of the Axl family and they play essential roles in spermatogenesis, immunoregulation, and phagocytosis.Tyro3 was expressed at high levels during postnatal development and in the adult in the cortex.Tyro3 and Gas6 have neurotrophic roles in the nervous system.In addition, the signalling interactions of Axl and Tyro3 may play roles in tumourigenesis, inflammation as well as other cell proliferative diseases.