ERBB3 Antikörper
Kurzübersicht für ERBB3 Antikörper (ABIN7505979)
Target
Alle ERBB3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Anti-Hu HER3 Purified
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Produktmerkmale
- The mouse monoclonal antibody H3Mab-17 recognizes an extracellular epitope on human HER3 (erbB3), a member of EGFR family of receptor tyrosine kinases, which is overexpressed in many cancers.
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Aufreinigung
- Purified by protein-A affinity chromatography.
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Immunogen
- HER3-transfected CHO cells
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Isotyp
- IgG2a, kappa
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anti-Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (AA 24-55), (N-Term) antibody
ERBB3 Reaktivität: Human, Maus WB, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB01467 unconjugated
anti-Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (AA 707-964) antibodyERBB3 Reaktivität: Maus IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (AA 1-130) antibodyERBB3 Reaktivität: Human WB, ELISA, IHC (p) Wirt: Maus Monoclonal 2E9 unconjugated
anti-Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (pTyr1289) antibodyERBB3 Reaktivität: Human WB, IF (p), IF (cc), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) antibodyERBB3 Reaktivität: Human WB, IP, IHC (fro), IHC (f) Wirt: Maus Monoclonal RTJ-1 unconjugated
anti-Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (AA 24-55) antibodyERBB3 Reaktivität: Human, Maus WB, IHC, ELISA, FACS Wirt: Kaninchen Polyclonal unconjugated
anti-Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (C-Term) antibodyVerified ERBB3 Reaktivität: Human IHC, ELISA, IF, FACS Wirt: Ziege Polyclonal unconjugated
anti-Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (pTyr1289) antibodyERBB3 Reaktivität: Human WB, DB Wirt: Kaninchen Polyclonal RB25837 unconjugated
anti-Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (AA 1175-1275) antibodyERBB3 Reaktivität: Human IHC, ELISA Wirt: Maus Monoclonal 3F10F6 unconjugated
anti-Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3) (AA 22-369) antibodyERBB3 Reaktivität: Human ELISA, ICC Wirt: Maus Monoclonal 2F9 unconjugated
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Applikationshinweise
- Flow cytometry: Recommended dilution: 1-5 μg/mL.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Do not freeze
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Store at 2-8°C. Do not freeze.
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- ERBB3 (Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3))
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Andere Bezeichnung
- HER3
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Hintergrund
- Erb-b2 receptor tyrosine kinase 3,HER3 (ERBB3) is a transmembrane protein of the epidermal growth factor receptor family, although it does not have an active tyrosine kinase domain. It can bind its ligand, but for further signaling it needs heterodimerization with other receptor tyrosine kinases of EGFR family. Overexpression of HER3 has been observed in many carcinomas. Activity of HER3 can be modulated by one of its isoforms, that is secreted from the cell, as its lacks the transmembrane domain.,ERBB3, FERLK, LCCS2
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Gen-ID
- 2065
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UniProt
- P21860
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Pathways
- RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung
Target
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