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Integrin alpha 1 Antikörper

ITGA1 Reaktivität: Human, Non-Human Primate FACS, IP, IHC (fro) Wirt: Maus Monoclonal TS2-7 unconjugated
Produktnummer ABIN7505935
  • Target Alle Integrin alpha 1 (ITGA1) Antikörper anzeigen
    Integrin alpha 1 (ITGA1)
    Reaktivität
    • 67
    • 34
    • 21
    • 3
    • 1
    Human, Non-Human Primate
    Wirt
    • 53
    • 16
    • 4
    • 1
    • 1
    Maus
    Klonalität
    • 58
    • 17
    Monoklonal
    Konjugat
    • 34
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Integrin alpha 1 Antikörper ist unkonjugiert
    Applikation
    • 51
    • 24
    • 23
    • 15
    • 13
    • 13
    • 13
    • 7
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Verwendungszweck
    Anti-Hu CD49a Purified
    Spezifität
    The mouse monoclonal antibody TS2/7 recognizes an extracellular epitope of CD49a, the alpha 1 chain of VLA integrin complex, that serves as an adhesion receptor for collagen IV and laminin 1.
    Aufreinigung
    Purified by protein-A affinity chromatography.
    Immunogen
    human CTL line
    Klon
    TS2-7
    Isotyp
    IgG1
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  • Applikationshinweise
    Flow cytometry: Recommended dilution: 1-4 μg/mL.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2-8°C. Do not freeze.
  • Target
    Integrin alpha 1 (ITGA1)
    Andere Bezeichnung
    CD49a (ITGA1 Produkte)
    Synonyme
    CD49A antikoerper, E130012M19Rik antikoerper, Vla1 antikoerper, CD49a antikoerper, VLA1 antikoerper, integrin alpha 1 antikoerper, integrin subunit alpha 1 antikoerper, Itga1 antikoerper, ITGA1 antikoerper
    Hintergrund
    Integrin subunit alpha 1,CD49a is the alpha 1 chain of VLA integrin complex (together with CD29, serving as the beta 1 chain), and is expressed on activated T cells, monocytes, NK cells, cultured neuronal cells, melanoma cells, mesenchymal cells (including smooth muscle cells), fibroblasts, hepatocytes, and microvascular endothelium. It binds to collagen IV and laminin 1. It is important for leukocyte migration into tissues. It is upregulated in inflammatory tissues, such as inflammed intestine.,alpha 1 integrin, VLA-1 alpha, ITGA1
    Gen-ID
    3672
    UniProt
    P56199
    Pathways
    EGFR Signaling Pathway, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex
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