Integrin alpha 1 Antikörper (AA 727-755)

Produktnummer ABIN652761

Zitiert in 1 Publikation. Der Kaninchen Polyklonal anti-Integrin alpha 1 Antikörper (Klon RB23364) (ABIN652761) detektiert spezifisch Integrin alpha 1 in WB und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für Integrin alpha 1 Antikörper (AA 727-755) (ABIN652761)

Target: Integrin alpha 1 (ITGA1)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Integrin alpha 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB23364

Produktdetails anti-Integrin alpha 1 Antikörper

Bindungsspezifität: AA 727-755

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ITGA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 727-755 amino acids from the Central region of human ITGA1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-Integrin alpha 1 Antikörper (ABIN652761)

Gutiérrez-Franco, Costa, Eixarch, Castillo, Medina-Rodríguez, Bribián, de Castro, Montalban, Espejo: "Differential expression of sema3A and sema7A in a murine model of multiple sclerosis: Implications for a therapeutic design." in: Clinical immunology (Orlando, Fla.), Vol. 163, pp. 22-33, (2016) (PubMed).

Details zu Integrin alpha 1

Target: Integrin alpha 1 (ITGA1)

Andere Bezeichnung: ITGA1

Hintergrund: ITGA1 is the alpha 1 subunit of integrin receptors. This protein heterodimerizes with the beta 1 subunit to form a cell-surface receptor for collagen and laminin. The heterodimeric receptor is involved in cell-cell adhesion and may play a role in inflammation and fibrosis. The alpha 1 subunit contains an inserted (I) von Willebrand factor type I domain which is thought to be involved in collagen binding.

Molekulargewicht: 130848

Gen-ID: 3672

NCBI Accession: NP_852478

UniProt: P56199

Pathways: EGFR Signaling Pathway, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex