Der Maus Monoklonal anti-FCRL4 Antikörper (Klon A1) (ABIN7505906) detektiert spezifisch FCRL4 in FACS und IHC (fro).
Dieser Antikörper reagiert spezifisch mit Proben aus Human.
The mouse monoclonal antibody A1 recognizes an epitope within extracellular domain of CD307d, a transmembrane glycoprotein expressed mainly on memory B cells.
Aufreinigung
Purified by protein-A affinity chromatography.
Immunogen
DNA-immunization followed by a boost with CD307d-transfected cells
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Do not freeze
Lagerung
4 °C
Informationen zur Lagerung
Store at 2-8°C. Do not freeze.
Target
FCRL4
(Fc Receptor-Like 4 (FCRL4))
Andere Bezeichnung
CD307d
Hintergrund
Fc receptor like 4,CD307d is a type I transmembrane glycoprotein of the Fc receptor family. It contains two ITIM motifs and one ITSM motif in its cytoplasmic domain. CD307d is expressed mainly on the surface of memory B cells in mucosa-associated lymphoid tissues. It binds to aggregated immunoglobulin molecules (IgA, IgG). Defects of CD307d may play a role in HIV-induced memory B cell dysfunction.,FcRL4, FCRH4, IRTA1