Synonyms: CD307d,Fc receptor homolog 4,Fc receptor like 4 ,Fc receptor like protein 4,Fc receptor-like protein 4,FcR like protein 4,FcR-like protein 4,FcRH4,FcRL4,FCRL4,hIFGP2,IFGP family protein 2,IGFP2,Immune receptor translocation associated protein 1,Immune receptor translocation-associated protein 1,Immunoglobulin superfamily receptor translocation associated 1,Immunoglobulin superfamily receptor translocation associated gene 1,IRTA1
Background: This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein has four extracellular C2-type immunoglobulin domains, a transmembrane domain and a cytoplasmic domain that contains three immune-receptor tyrosine-based inhibitory motifs. This protein may play a role in the function of memory B-cells in the epithelia. Aberrations in the chromosomal region encoding this gene are associated with non-Hodgkin lymphoma and multiple myeloma.