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BTLA Antikörper

BTLA Reaktivität: Human, Non-Human Primate FACS Wirt: Maus Monoclonal MIH26 unconjugated
Produktnummer ABIN7505891
  • Target Alle BTLA Antikörper anzeigen
    BTLA (B and T Lymphocyte Associated (BTLA))
    Reaktivität
    • 59
    • 35
    • 3
    • 2
    • 1
    • 1
    Human, Non-Human Primate
    Wirt
    • 33
    • 28
    • 11
    • 4
    • 1
    • 1
    Maus
    Klonalität
    • 44
    • 32
    • 2
    Monoklonal
    Konjugat
    • 44
    • 7
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser BTLA Antikörper ist unkonjugiert
    Applikation
    • 50
    • 44
    • 27
    • 13
    • 13
    • 8
    • 7
    • 6
    • 5
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    Flow Cytometry (FACS)
    Verwendungszweck
    Anti-Hu CD272 Purified
    Spezifität
    The mouse monoclonal antibody MIH26 recognizes an extracellular epitope of CD272, a transmembrane glycoprotein serving as a negative regulator of the activation in various leukocyte types.
    Aufreinigung
    Purified by protein-A affinity chromatography.
    Immunogen
    cells transfected with human CD272
    Klon
    MIH26
    Isotyp
    IgG2a kappa
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  • Applikationshinweise
    Flow cytometry: Recommended dilution: 2-5 μg/mL.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2-8°C. Do not freeze.
  • Target
    BTLA (B and T Lymphocyte Associated (BTLA))
    Andere Bezeichnung
    CD272 (BTLA Produkte)
    Synonyme
    BTLA antikoerper, BTLA1 antikoerper, CD272 antikoerper, A630002H24 antikoerper, B and T lymphocyte associated antikoerper, BTLA antikoerper, Btla antikoerper
    Hintergrund
    B and T lymphocyte associated,CD272, a type I transmembrane glycoprotein, contains in its intracellular domain two ITIM sequences, which are upon CD272 triggering phosphorylated and recruit SHP phosphatases to attenuate cell activation. CD272 is expressed on B and T lymphocytes, NK cells, dendritic cells, and macrophages, and its ligand is CD270. Defects in CD272-CD270 inhibitory mechanism lead to autoimmune diseases. Overexpression of CD272 is a marker of tolerant T cells.,BTLA1
    Gen-ID
    151888
    UniProt
    Q7Z6A9
    Pathways
    Cancer Immune Checkpoints
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