BTLA Antikörper
Kurzübersicht für BTLA Antikörper (ABIN7505891)
Target
Alle BTLA Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Anti-Hu CD272 Purified
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Produktmerkmale
- The mouse monoclonal antibody MIH26 recognizes an extracellular epitope of CD272, a transmembrane glycoprotein serving as a negative regulator of the activation in various leukocyte types.
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Aufreinigung
- Purified by protein-A affinity chromatography.
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Immunogen
- cells transfected with human CD272
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Isotyp
- IgG2a, kappa
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Applikationshinweise
- Flow cytometry: Recommended dilution: 2-5 μg/mL.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Do not freeze
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Store at 2-8°C. Do not freeze.
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- BTLA (B and T Lymphocyte Associated (BTLA))
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Andere Bezeichnung
- CD272
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Hintergrund
- B and T lymphocyte associated,CD272, a type I transmembrane glycoprotein, contains in its intracellular domain two ITIM sequences, which are upon CD272 triggering phosphorylated and recruit SHP phosphatases to attenuate cell activation. CD272 is expressed on B and T lymphocytes, NK cells, dendritic cells, and macrophages, and its ligand is CD270. Defects in CD272-CD270 inhibitory mechanism lead to autoimmune diseases. Overexpression of CD272 is a marker of tolerant T cells.,BTLA1
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Gen-ID
- 151888
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UniProt
- Q7Z6A9
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Pathways
- Cancer Immune Checkpoints
Target
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