BTLA Antikörper

Produktnummer ABIN7505891

Dieses Anti-BTLA-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von BTLA in FACS. Geeignet für Human und Non-Human Primate.

Kurzübersicht für BTLA Antikörper (ABIN7505891)

Target: BTLA (B and T Lymphocyte Associated (BTLA))

Reaktivität: Human, Non-Human Primate

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser BTLA Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Klon: MIH26

Produktdetails anti-BTLA Antikörper

Verwendungszweck: Anti-Hu CD272 Purified

Spezifität: The mouse monoclonal antibody MIH26 recognizes an extracellular epitope of CD272, a transmembrane glycoprotein serving as a negative regulator of the activation in various leukocyte types.

Aufreinigung: Purified by protein-A affinity chromatography.

Immunogen: cells transfected with human CD272

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise: Flow cytometry: Recommended dilution: 2-5 μg/mL.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Do not freeze.

Details zu BTLA

Target: BTLA (B and T Lymphocyte Associated (BTLA))

Andere Bezeichnung: CD272

Hintergrund: B and T lymphocyte associated,CD272, a type I transmembrane glycoprotein, contains in its intracellular domain two ITIM sequences, which are upon CD272 triggering phosphorylated and recruit SHP phosphatases to attenuate cell activation. CD272 is expressed on B and T lymphocytes, NK cells, dendritic cells, and macrophages, and its ligand is CD270. Defects in CD272-CD270 inhibitory mechanism lead to autoimmune diseases. Overexpression of CD272 is a marker of tolerant T cells.,BTLA1

Gen-ID: 151888

UniProt: Q7Z6A9

Pathways: Cancer Immune Checkpoints