Rekombinanter MAGEA3 Antikörper

Produktnummer ABIN7487738

Dieses Kaninchen Chimeric-Antikörper erkennt spezifisch MAGEA3 in WB, ELISA, IHC, FACS und IP. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Rekombinanter MAGEA3 Antikörper (ABIN7487738)

Target: MAGEA3 (Melanoma Antigen Family A, 3 (MAGEA3))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Chimeric

Konjugat: Dieser MAGEA3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunoprecipitation (IP)

Klon: 21B4

Produktdetails anti-MAGEA3 Antikörper

Verwendungszweck: Anti-MAGEA3 [21B4], Rabbit IgG, kappa

Spezifität: This antibody binds human MAGEA3 and MAGEA6, but does not cross react with other members of the MAGE family like MAGE-A1, MAGE-A4 and MAGE-A10. MAGE-A3 is a tumor specific antigen and it is expressed on many tumors like melanoma, non-small cell lung cancer, hematologic malignancies, and others.

Produktmerkmale:

Original Species of Ab: Human

Original Format of Ab: IgG1

Aufreinigung: Protein A affinity purified

Immunogen: The original antibody was isolated from a patient suffering from a tumor expressing a tumor specific antigen like MAGE-A3.

Isotyp: IgG kappa

Anwendungsinformationen

Applikationshinweise: The binding specificity of this antibody towards MAGE-A3 was determined using ELISA. The original antibody cross reacts with MAGEA6 but does not react with other members of the MAGE family in an ELISA or western blot assay. This antibody was used in the detection of HEK293T cells expressing MAGEA3 and MAGEA6 using flow cytometry. The original IgG1 antibody was capable of immunoprecipitating MAGE-A3 from lysates of SK-MEL-37 cells endogenously expressing MAGEA3. The original antibody was also used in the immunohistochemical staining of tissues form normal testis and squamous cell carcinoma of the lung (US20140093514).

Kommentare:

This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG1 format for improved compatibility with existing reagents assays and techniques.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Details zu MAGEA3

Target: MAGEA3 (Melanoma Antigen Family A, 3 (MAGEA3))

Andere Bezeichnung: MAGEA3

Hintergrund: MAGE-3, MAGE3, MAGE 3, CT1.3, MAGE-3 antigen, Melanoma-associated antigen 3, Antigen MZ2-D, Cancer/testis antigen 1.3, MAGEA6, MAGE6, Melanoma-associated antigen 6, Cancer/testis antigen 1.6, CT1.6, MAGE-6 antigen, MAGE3B antigen

UniProt: P43357, P43360