Rekombinanter CD47 Antikörper

Produktnummer ABIN7487702

Dieses Ratte Monoklonal-Antikörper erkennt spezifisch CD47 in IF und BP. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Rekombinanter CD47 Antikörper (ABIN7487702)

Target: CD47

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser CD47 Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF), Blocking Peptide (BP)

Klon: MIAP430

Produktdetails anti-CD47 Antikörper

Verwendungszweck: Anti-CD47 [mIAP430], Rat IgG2a, kappa

Spezifität: This antibody recognises CD47 which is a a multitransmembrane glycoprotein widely expressed on all hematopoietic cells and most other cell types. It is involved in cell adhesion, Ca2+ influx, platelet activation and peripheral mononuclear neutrophils migration across endothelial and epithelial monolayers.

Produktmerkmale:

Original Species of Ab: Mouse

Original Format of Ab: IgG2a

Aufreinigung: Protein A affinity purified

Immunogen: This antibody was raised by immunising IAP-deficient mice with purified human placental CD47.

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise: This antibody can be used to investigate the role of the CD47 receptor. mIAP430 was first used to visualise the distribution of CD47 on fusing macrophages (Han et al., 2000). Further, it was demonstrated that this antibody can block fusion of macrophages by blocking CD47 and preventing the binding of this receptor with MFR (Han et al., 2000).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Details zu CD47

Target: CD47

Andere Bezeichnung: CD47

Hintergrund: IAP, C5/D5, Leukocyte surface antigen CD47, Antigenic surface determinant protein OA3, Integrin-associated protein, Protein MER6

UniProt: Q08722